cardiolipin acyl-chain remodeling Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. (Gene Ontology, GO_0035965)
External Link	http://amigo.geneontology.org/amigo/term/GO:0035965
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Genes

5 genes participating in the cardiolipin acyl-chain remodeling biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
LCLAT1	lysocardiolipin acyltransferase 1
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)
TAFAZZIN	tafazzin, phospholipid-lysophospholipid transacylase
THEM5	thioesterase superfamily member 5