cardiomyopathy Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).|A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. (Experimental Factor Ontology, EFO_0000318)
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Genes

32 genes associated with the disease cardiomyopathy in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTC1 actin, alpha, cardiac muscle 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANKH ANKH inorganic pyrophosphate transport regulator
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DMD dystrophin
DSC2 desmocollin 2
DSG2 desmoglein 2
DSP desmoplakin
HFE hemochromatosis
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
JUP junction plakoglobin
LMNA lamin A/C
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MYBPC3 myosin binding protein C, cardiac
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGF nerve growth factor (beta polypeptide)
PKP2 plakophilin 2
PLN phospholamban
SOD2 superoxide dismutase 2, mitochondrial
TCAP titin-cap
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TPM1 tropomyosin 1 (alpha)