| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the carmustine-6883 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| AK2 | adenylate kinase 2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ATM | ATM serine/threonine kinase |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| BAX | BCL2-associated X protein |
| BCL2L1 | BCL2-like 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CD47 | CD47 molecule |
| CDV3 | CDV3 homolog (mouse) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNN2 | calponin 2 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CPM | carboxypeptidase M |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FCF1 | FCF1 rRNA-processing protein |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLCN | folliculin |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLRA3 | glycine receptor, alpha 3 |
| GLTP | glycolipid transfer protein |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPR176 | G protein-coupled receptor 176 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIRA | histone cell cycle regulator |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| JUN | jun proto-oncogene |
| LDLR | low density lipoprotein receptor |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC40 | leucine rich repeat containing 40 |
| MED18 | mediator complex subunit 18 |
| MED6 | mediator complex subunit 6 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCNX | pecanex homolog (Drosophila) |
| PFDN6 | prefoldin subunit 6 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 |
| POLH | polymerase (DNA directed), eta |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB2A | RAB2A, member RAS oncogene family |
| RAB3B | RAB3B, member RAS oncogene family |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RIOK3 | RIO kinase 3 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RREB1 | ras responsive element binding protein 1 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNX13 | sorting nexin 13 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SRRT | serrate, RNA effector molecule |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TOR4A | torsin family 4, member A |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM16 | tripartite motif containing 16 |
| TUBD1 | tubulin, delta 1 |
| UNKL | unkempt family zinc finger-like |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| YIPF5 | Yip1 domain family, member 5 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF430 | zinc finger protein 430 |
| ZNF652 | zinc finger protein 652 |
| ZNF665 | zinc finger protein 665 |
| ZNF91 | zinc finger protein 91 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
| Symbol | Name |
|---|---|
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AMT | aminomethyltransferase |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPC | centromere protein C |
| CLDN14 | claudin 14 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COL21A1 | collagen, type XXI, alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DENND2D | DENN/MADD domain containing 2D |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EGR2 | early growth response 2 |
| FAM131B | family with sequence similarity 131, member B |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FNDC4 | fibronectin type III domain containing 4 |
| FUZ | fuzzy planar cell polarity protein |
| GAB2 | GRB2-associated binding protein 2 |
| GALK1 | galactokinase 1 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| HOXA1 | homeobox A1 |
| HOXC10 | homeobox C10 |
| HOXC4 | homeobox C4 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT81 | intraflagellar transport 81 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM4D | lysine (K)-specific demethylase 4D |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT15 | keratin 15, type I |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIPG | lipase, endothelial |
| LOC730101 | uncharacterized LOC730101 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PALMD | palmdelphin |
| PER3 | period circadian clock 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHF14 | PHD finger protein 14 |
| PMCH | pro-melanin-concentrating hormone |
| PRR15L | proline rich 15-like |
| PRSS22 | protease, serine, 22 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RNF43 | ring finger protein 43 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SETBP1 | SET binding protein 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC30A4 | solute carrier family 30 (zinc transporter), member 4 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPATA7 | spermatogenesis associated 7 |
| SPIDR | scaffolding protein involved in DNA repair |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST5 | suppression of tumorigenicity 5 |
| ST7L | suppression of tumorigenicity 7 like |
| TBX19 | T-box 19 |
| TESK2 | testis-specific kinase 2 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TRIM9 | tripartite motif containing 9 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC31 | tetratricopeptide repeat domain 31 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBG2 | tubulin, gamma 2 |
| VGF | VGF nerve growth factor inducible |
| WDR60 | WD repeat domain 60 |
| XAB2 | XPA binding protein 2 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF365 | zinc finger protein 365 |
| ZNF813 | zinc finger protein 813 |
| ZNF862 | zinc finger protein 862 |