carmustine-6883 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the carmustine-6883 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM1 acyl-CoA synthetase medium-chain family member 1
AK2 adenylate kinase 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ATM ATM serine/threonine kinase
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAX BCL2-associated X protein
BCL2L1 BCL2-like 1
C11ORF30 chromosome 11 open reading frame 30
C4ORF29 chromosome 4 open reading frame 29
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CD47 CD47 molecule
CDV3 CDV3 homolog (mouse)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNN2 calponin 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CPM carboxypeptidase M
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EYA4 EYA transcriptional coactivator and phosphatase 4
FCF1 FCF1 rRNA-processing protein
FKBP14 FK506 binding protein 14, 22 kDa
FLCN folliculin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRA3 glycine receptor, alpha 3
GLTP glycolipid transfer protein
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR176 G protein-coupled receptor 176
GUSBP3 glucuronidase, beta pseudogene 3
HAUS5 HAUS augmin-like complex, subunit 5
HIRA histone cell cycle regulator
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
JUN jun proto-oncogene
LDLR low density lipoprotein receptor
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC40 leucine rich repeat containing 40
MED18 mediator complex subunit 18
MED6 mediator complex subunit 6
MET MET proto-oncogene, receptor tyrosine kinase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCNX pecanex homolog (Drosophila)
PFDN6 prefoldin subunit 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
POLH polymerase (DNA directed), eta
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PVT1 Pvt1 oncogene (non-protein coding)
RAB2A RAB2A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RFC2 replication factor C (activator 1) 2, 40kDa
RIOK3 RIO kinase 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL23AP32 ribosomal protein L23a pseudogene 32
RREB1 ras responsive element binding protein 1
RSL1D1 ribosomal L1 domain containing 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMG7 SMG7 nonsense mediated mRNA decay factor
SNX13 sorting nexin 13
SPATS2L spermatogenesis associated, serine-rich 2-like
SRRT serrate, RNA effector molecule
SS18 synovial sarcoma translocation, chromosome 18
SUN1 Sad1 and UNC84 domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TOR4A torsin family 4, member A
TRAK1 trafficking protein, kinesin binding 1
TRIM16 tripartite motif containing 16
TUBD1 tubulin, delta 1
UNKL unkempt family zinc finger-like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR76 WD repeat domain 76
YIPF5 Yip1 domain family, member 5
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF205 zinc finger protein 205
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF91 zinc finger protein 91
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AMT aminomethyltransferase
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C14ORF79 chromosome 14 open reading frame 79
C19ORF57 chromosome 19 open reading frame 57
C1ORF105 chromosome 1 open reading frame 105
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
CARD8 caspase recruitment domain family, member 8
CCRL2 chemokine (C-C motif) receptor-like 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CENPC centromere protein C
CLDN14 claudin 14
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL21A1 collagen, type XXI, alpha 1
CSF1R colony stimulating factor 1 receptor
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DENND2D DENN/MADD domain containing 2D
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGR2 early growth response 2
FAM131B family with sequence similarity 131, member B
FBXL15 F-box and leucine-rich repeat protein 15
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FNDC4 fibronectin type III domain containing 4
FUZ fuzzy planar cell polarity protein
GAB2 GRB2-associated binding protein 2
GALK1 galactokinase 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HOXA1 homeobox A1
HOXC10 homeobox C10
HOXC4 homeobox C4
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT81 intraflagellar transport 81
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM4D lysine (K)-specific demethylase 4D
KDM5C lysine (K)-specific demethylase 5C
KRT15 keratin 15, type I
LHX6 LIM homeobox 6
LIME1 Lck interacting transmembrane adaptor 1
LIPG lipase, endothelial
LOC730101 uncharacterized LOC730101
LRRK1 leucine-rich repeat kinase 1
MAP3K7CL MAP3K7 C-terminal like
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
NARFL nuclear prelamin A recognition factor-like
NDE1 nudE neurodevelopment protein 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
NUP62CL nucleoporin 62kDa C-terminal like
ORAI3 ORAI calcium release-activated calcium modulator 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALMD palmdelphin
PER3 period circadian clock 3
PGPEP1 pyroglutamyl-peptidase I
PHF14 PHD finger protein 14
PMCH pro-melanin-concentrating hormone
PRR15L proline rich 15-like
PRSS22 protease, serine, 22
PSRC1 proline/serine-rich coiled-coil 1
RNF43 ring finger protein 43
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETBP1 SET binding protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIRAL2 SIR2 antiphage like 2
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SOBP sine oculis binding protein homolog (Drosophila)
SPATA7 spermatogenesis associated 7
SPIDR scaffolding protein involved in DNA repair
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
ST7L suppression of tumorigenicity 7 like
TBX19 T-box 19
TESK2 testis-specific kinase 2
TMEM8B transmembrane protein 8B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRIM9 tripartite motif containing 9
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC31 tetratricopeptide repeat domain 31
TTLL7 tubulin tyrosine ligase-like family member 7
TUBG2 tubulin, gamma 2
VGF VGF nerve growth factor inducible
WDR60 WD repeat domain 60
XAB2 XPA binding protein 2
ZBTB39 zinc finger and BTB domain containing 39
ZFYVE16 zinc finger, FYVE domain containing 16
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF365 zinc finger protein 365
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862