carmustine-6888 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carmustine-6888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APOC1 apolipoprotein C-I
ARHGAP35 Rho GTPase activating protein 35
ATG2A autophagy related 2A
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF61 chromosome 1 open reading frame 61
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CD58 CD58 molecule
CD8A CD8a molecule
CGREF1 cell growth regulator with EF-hand domain 1
COPA coatomer protein complex, subunit alpha
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DMXL2 Dmx-like 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
GAMT guanidinoacetate N-methyltransferase
GAS2 growth arrest-specific 2
GCLM glutamate-cysteine ligase, modifier subunit
GLS2 glutaminase 2 (liver, mitochondrial)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HABP4 hyaluronan binding protein 4
HFE hemochromatosis
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AJ histone cluster 1, H2aj
HMOX1 heme oxygenase 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLF6 Kruppel-like factor 6
KLHL28 kelch-like family member 28
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LMF1 lipase maturation factor 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC41 leucine rich repeat containing 41
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MARK4 MAP/microtubule affinity-regulating kinase 4
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MPPE1 metallophosphoesterase 1
MUC3B mucin 3B, cell surface associated
NAAA N-acylethanolamine acid amidase
PADI1 peptidyl arginine deiminase, type I
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF14 PHD finger protein 14
PICK1 protein interacting with PRKCA 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAUR plasminogen activator, urokinase receptor
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPT2 palmitoyl-protein thioesterase 2
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRLR prolactin receptor
PTBP3 polypyrimidine tract binding protein 3
RAB35 RAB35, member RAS oncogene family
RARG retinoic acid receptor, gamma
RGS12 regulator of G-protein signaling 12
RNF19B ring finger protein 19B
RUFY3 RUN and FYVE domain containing 3
SH3BP2 SH3-domain binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIK2 salt-inducible kinase 2
SLC16A4 solute carrier family 16, member 4
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
STK24 serine/threonine kinase 24
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCP11L1 t-complex 11, testis-specific-like 1
TMCO3 transmembrane and coiled-coil domains 3
TMPRSS2 transmembrane protease, serine 2
TOX4 TOX high mobility group box family member 4
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TXNRD1 thioredoxin reductase 1
USP48 ubiquitin specific peptidase 48
VARS valyl-tRNA synthetase
YY1 YY1 transcription factor
ZFP30 ZFP30 zinc finger protein
ZFPL1 zinc finger protein-like 1
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACAD10 acyl-CoA dehydrogenase family, member 10
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMPD2 adenosine monophosphate deaminase 2
APOD apolipoprotein D
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AUTS2 autism susceptibility candidate 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BGLAP bone gamma-carboxyglutamate (gla) protein
C2ORF54 chromosome 2 open reading frame 54
C8ORF44 chromosome 8 open reading frame 44
CAMKMT calmodulin-lysine N-methyltransferase
CCDC7 coiled-coil domain containing 7
CCDC88C coiled-coil domain containing 88C
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLEC4E C-type lectin domain family 4, member E
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRY2 cryptochrome circadian clock 2
CXXC4 CXXC finger protein 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DIXDC1 DIX domain containing 1
EVPL envoplakin
FADS2 fatty acid desaturase 2
FAM169A family with sequence similarity 169, member A
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GRB7 growth factor receptor-bound protein 7
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AI histone cluster 1, H2ai
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
INPP5J inositol polyphosphate-5-phosphatase J
IRF6 interferon regulatory factor 6
KIAA0125 KIAA0125
KIF16B kinesin family member 16B
KLHL25 kelch-like family member 25
LHX6 LIM homeobox 6
LOC100287590 uncharacterized LOC100287590
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYRM9 LYR motif containing 9
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYL5 myosin, light chain 5, regulatory
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPY1R neuropeptide Y receptor Y1
NT5DC3 5'-nucleotidase domain containing 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PADI3 peptidyl arginine deiminase, type III
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PDZRN3 PDZ domain containing ring finger 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF21A PHD finger protein 21A
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G10 phospholipase A2, group X
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMCH pro-melanin-concentrating hormone
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT2 protein-O-mannosyltransferase 2
PRICKLE3 prickle homolog 3 (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RFTN1 raftlin, lipid raft linker 1
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RPH3AL rabphilin 3A-like (without C2 domains)
RPL13P5 ribosomal protein L13 pseudogene 5
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SALL2 spalt-like transcription factor 2
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SECTM1 secreted and transmembrane 1
SH2D4A SH2 domain containing 4A
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOBP sine oculis binding protein homolog (Drosophila)
SREBF1 sterol regulatory element binding transcription factor 1
SRPX sushi-repeat containing protein, X-linked
STK25 serine/threonine kinase 25
SULT4A1 sulfotransferase family 4A, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TDRD1 tudor domain containing 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VAX2 ventral anterior homeobox 2
XK X-linked Kx blood group
ZNF324 zinc finger protein 324
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2