carteolol-1340 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carteolol-1340 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANKRD26 ankyrin repeat domain 26
AQP1 aquaporin 1 (Colton blood group)
ARHGAP10 Rho GTPase activating protein 10
BAD BCL2-associated agonist of cell death
BIK BCL2-interacting killer (apoptosis-inducing)
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTN3A1 butyrophilin, subfamily 3, member A1
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
CASP4 caspase 4, apoptosis-related cysteine peptidase
CRTC1 CREB regulated transcription coactivator 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEAF1 DEAF1 transcription factor
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DMWD dystrophia myotonica, WD repeat containing
DNMBP dynamin binding protein
EMILIN2 elastin microfibril interfacer 2
ETAA1 Ewing tumor-associated antigen 1
FBRS fibrosin
FH fumarate hydratase
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FUZ fuzzy planar cell polarity protein
G6PC3 glucose 6 phosphatase, catalytic, 3
GAMT guanidinoacetate N-methyltransferase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPSM3 G-protein signaling modulator 3
GRM1 glutamate receptor, metabotropic 1
HIST1H2AJ histone cluster 1, H2aj
HTATSF1 HIV-1 Tat specific factor 1
IL22 interleukin 22
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0319L KIAA0319-like
KRAS Kirsten rat sarcoma viral oncogene homolog
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIG3 ligase III, DNA, ATP-dependent
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MAST2 microtubule associated serine/threonine kinase 2
METTL7A methyltransferase like 7A
MLF1 myeloid leukemia factor 1
MPZL1 myelin protein zero-like 1
MTCP1 mature T-cell proliferation 1
MVD mevalonate (diphospho) decarboxylase
MXD4 MAX dimerization protein 4
MYOF myoferlin
MZF1 myeloid zinc finger 1
NCAPH2 non-SMC condensin II complex, subunit H2
NCS1 neuronal calcium sensor 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM5 PDZ and LIM domain 5
PLSCR3 phospholipid scramblase 3
PNMA1 paraneoplastic Ma antigen 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POMZP3 POM121 and ZP3 fusion
PRKDC protein kinase, DNA-activated, catalytic polypeptide
SEC23IP SEC23 interacting protein
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
STAT5A signal transducer and activator of transcription 5A
SYMPK symplekin
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBC1D4 TBC1 domain family, member 4
TMEM63A transmembrane protein 63A
TOP3A topoisomerase (DNA) III alpha
TRD T cell receptor delta locus
TRMT61A tRNA methyltransferase 61A
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBOX5 U-box domain containing 5
UNC13B unc-13 homolog B (C. elegans)
USP34 ubiquitin specific peptidase 34
VPRBP Vpr (HIV-1) binding protein
WDTC1 WD and tetratricopeptide repeats 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZBTB44 zinc finger and BTB domain containing 44
ZFPL1 zinc finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF337 zinc finger protein 337
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACP6 acid phosphatase 6, lysophosphatidic
ACPP acid phosphatase, prostate
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBR apolipoprotein B receptor
APOLD1 apolipoprotein L domain containing 1
ASB6 ankyrin repeat and SOCS box containing 6
BAK1 BCL2-antagonist/killer 1
BATF basic leucine zipper transcription factor, ATF-like
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF71 chromosome 11 open reading frame 71
C4ORF29 chromosome 4 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC6 coiled-coil domain containing 6
CD3D CD3d molecule, delta (CD3-TCR complex)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
COL9A2 collagen, type IX, alpha 2
CTNNBL1 catenin, beta like 1
CTPS2 CTP synthase 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAL4 dynein, axonemal, light chain 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSE dermatan sulfate epimerase
DVL1 dishevelled segment polarity protein 1
E4F1 E4F transcription factor 1
ELP6 elongator acetyltransferase complex subunit 6
EPHB6 EPH receptor B6
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC5 exocyst complex component 5
FAM114A1 family with sequence similarity 114, member A1
FAM53B family with sequence similarity 53, member B
GIN1 gypsy retrotransposon integrase 1
GJA1 gap junction protein, alpha 1, 43kDa
GPALPP1 GPALPP motifs containing 1
GPR63 G protein-coupled receptor 63
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H2BI histone cluster 1, H2bi
HPSE heparanase
IFT46 intraflagellar transport 46
IGSF6 immunoglobulin superfamily, member 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5F inositol polyphosphate-5-phosphatase F
ISOC2 isochorismatase domain containing 2
LIG4 ligase IV, DNA, ATP-dependent
LRRC42 leucine rich repeat containing 42
LSP1 lymphocyte-specific protein 1
MBTD1 mbt domain containing 1
MCRS1 microspherule protein 1
MRPL44 mitochondrial ribosomal protein L44
MYO5C myosin VC
NMB neuromedin B
NSUN3 NOP2/Sun domain family, member 3
ODF2 outer dense fiber of sperm tails 2
PAQR4 progestin and adipoQ receptor family member IV
PHACTR1 phosphatase and actin regulator 1
POLM polymerase (DNA directed), mu
PSKH1 protein serine kinase H1
PTDSS2 phosphatidylserine synthase 2
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPP38 ribonuclease P/MRP 38kDa subunit
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCYL2 SCY1-like 2 (S. cerevisiae)
SERINC5 serine incorporator 5
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SPATA2L spermatogenesis associated 2-like
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STARD8 StAR-related lipid transfer (START) domain containing 8
TAOK1 TAO kinase 1
TASP1 taspase, threonine aspartase, 1
THBS3 thrombospondin 3
THOC6 THO complex 6
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM254 transmembrane protein 254
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM52 tripartite motif containing 52
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPAN32 tetraspanin 32
UNC119B unc-119 homolog B (C. elegans)
UNKL unkempt family zinc finger-like
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
WDR46 WD repeat domain 46
ZBTB10 zinc finger and BTB domain containing 10
ZMYM3 zinc finger, MYM-type 3
ZNF32 zinc finger protein 32
ZNF552 zinc finger protein 552
ZNF629 zinc finger protein 629
ZNF675 zinc finger protein 675