carteolol-3276 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carteolol-3276 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADGRL1 adhesion G protein-coupled receptor L1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKLE2 ankyrin repeat and LEM domain containing 2
ANTXR1 anthrax toxin receptor 1
ARHGAP33 Rho GTPase activating protein 33
ARL4C ADP-ribosylation factor-like 4C
ARNT aryl hydrocarbon receptor nuclear translocator
ASPH aspartate beta-hydroxylase
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C17ORF53 chromosome 17 open reading frame 53
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCPG1 cell cycle progression 1
CDC14B cell division cycle 14B
CDK20 cyclin-dependent kinase 20
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP250 centrosomal protein 250kDa
CEP41 centrosomal protein 41kDa
CLCN7 chloride channel, voltage-sensitive 7
CORT cortistatin
CTDNEP1 CTD nuclear envelope phosphatase 1
CTSF cathepsin F
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DZIP3 DAZ interacting zinc finger protein 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
FBXL15 F-box and leucine-rich repeat protein 15
FBXL18 F-box and leucine-rich repeat protein 18
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FSCN1 fascin actin-bundling protein 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPER1 G protein-coupled estrogen receptor 1
GPR137 G protein-coupled receptor 137
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC5 homeobox C5
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ICA1 islet cell autoantigen 1, 69kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KIAA0586 KIAA0586
KLHL23 kelch-like family member 23
LEPROT leptin receptor overlapping transcript
LIMCH1 LIM and calponin homology domains 1
LMO2 LIM domain only 2 (rhombotin-like 1)
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MDM4 MDM4, p53 regulator
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTM1 myotubularin 1
MYL10 myosin, light chain 10, regulatory
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCF4 neutrophil cytosolic factor 4, 40kDa
NLRX1 NLR family member X1
NPR2 natriuretic peptide receptor 2
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRPH peripherin
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PXDC1 PX domain containing 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIMS3 regulating synaptic membrane exocytosis 3
RIN2 Ras and Rab interactor 2
RIOK3 RIO kinase 3
RNF141 ring finger protein 141
RNF39 ring finger protein 39
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL10L ribosomal protein L10-like
S100A13 S100 calcium binding protein A13
S100A2 S100 calcium binding protein A2
SETD1B SET domain containing 1B
SGPL1 sphingosine-1-phosphate lyase 1
SIDT2 SID1 transmembrane family, member 2
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SSH3 slingshot protein phosphatase 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STK3 serine/threonine kinase 3
STYK1 serine/threonine/tyrosine kinase 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TLE2 transducin-like enhancer of split 2
TLE4 transducin-like enhancer of split 4
TMC5 transmembrane channel-like 5
TOP3B topoisomerase (DNA) III beta
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB1 zinc finger and BTB domain containing 1
ZNF419 zinc finger protein 419
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOLD1 apolipoprotein L domain containing 1
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCAS1 breast carcinoma amplified sequence 1
BCL2L2 BCL2-like 2
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
C5AR2 complement component 5a receptor 2
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC121 coiled-coil domain containing 121
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CEMIP cell migration inducing protein, hyaluronan binding
CIC capicua transcriptional repressor
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CLSTN2 calsyntenin 2
CUL9 cullin 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DEAF1 DEAF1 transcription factor
DSCAM Down syndrome cell adhesion molecule
EMID1 EMI domain containing 1
EML4 echinoderm microtubule associated protein like 4
EXD3 exonuclease 3'-5' domain containing 3
EXOC6B exocyst complex component 6B
FADS2 fatty acid desaturase 2
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FOSL1 FOS-like antigen 1
GAS2 growth arrest-specific 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST2H2AA3 histone cluster 2, H2aa3
HYI hydroxypyruvate isomerase (putative)
IFT81 intraflagellar transport 81
IGSF1 immunoglobulin superfamily, member 1
IRF7 interferon regulatory factor 7
KCNIP1 Kv channel interacting protein 1
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MRPS18C mitochondrial ribosomal protein S18C
MSI1 musashi RNA-binding protein 1
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PDE12 phosphodiesterase 12
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POM121 POM121 transmembrane nucleoporin
PRF1 perforin 1 (pore forming protein)
PRKCE protein kinase C, epsilon
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SHARPIN SHANK-associated RH domain interactor
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO1 slowmo homolog 1 (Drosophila)
SPAG7 sperm associated antigen 7
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN transgelin
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOM1 target of myb1 (chicken)
TRAIP TRAF interacting protein
TRIM21 tripartite motif containing 21
UNC93B1 unc-93 homolog B1 (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
WLS wntless Wnt ligand secretion mediator
ZNF552 zinc finger protein 552
ZSCAN2 zinc finger and SCAN domain containing 2