carteolol-4176 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the carteolol-4176 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACACB acetyl-CoA carboxylase beta
ACOX2 acyl-CoA oxidase 2, branched chain
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGRP agouti related neuropeptide
AKR1C4 aldo-keto reductase family 1, member C4
ALB albumin
ALPK1 alpha-kinase 1
APOL6 apolipoprotein L, 6
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
C14ORF1 chromosome 14 open reading frame 1
C6ORF10 chromosome 6 open reading frame 10
CALD1 caldesmon 1
CALML3 calmodulin-like 3
CD101 CD101 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CIITA class II, major histocompatibility complex, transactivator
CRISP2 cysteine-rich secretory protein 2
DMP1 dentin matrix acidic phosphoprotein 1
DTX2 deltex 2, E3 ubiquitin ligase
ELOVL2 ELOVL fatty acid elongase 2
F5 coagulation factor V (proaccelerin, labile factor)
FAIM2 Fas apoptotic inhibitory molecule 2
FAM49B family with sequence similarity 49, member B
FBLN1 fibulin 1
FGF6 fibroblast growth factor 6
FLT3LG fms-related tyrosine kinase 3 ligand
FSCN1 fascin actin-bundling protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
IZUMO4 IZUMO family member 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLK13 kallikrein-related peptidase 13
LAMB4 laminin, beta 4
LEF1 lymphoid enhancer-binding factor 1
LOC79999 uncharacterized LOC79999
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LUZP4 leucine zipper protein 4
MAGEC3 melanoma antigen family C3
MBD2 methyl-CpG binding domain protein 2
MED18 mediator complex subunit 18
MED25 mediator complex subunit 25
MID1 midline 1
MPZ myelin protein zero
MSR1 macrophage scavenger receptor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NTNG1 netrin G1
NUP88 nucleoporin 88kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OMD osteomodulin
PADI4 peptidyl arginine deiminase, type IV
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGB6 protocadherin gamma subfamily B, 6
PCNX pecanex homolog (Drosophila)
PDAP1 PDGFA associated protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PLEKHS1 pleckstrin homology domain containing, family S member 1
PML promyelocytic leukemia
PODNL1 podocan-like 1
PROL1 proline rich, lacrimal 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RABGAP1 RAB GTPase activating protein 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM26 RNA binding motif protein 26
RERE arginine-glutamic acid dipeptide (RE) repeats
RPL35A ribosomal protein L35a
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SIPA1 signal-induced proliferation-associated 1
SOX21 SRY (sex determining region Y)-box 21
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPN sialophorin
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN3 transgelin 3
TBX6 T-box 6
TEP1 telomerase-associated protein 1
TMPRSS4 transmembrane protease, serine 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TUBA3C tubulin, alpha 3c
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMPD1 adenosine monophosphate deaminase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARRB1 arrestin, beta 1
BLNK B-cell linker
C11ORF21 chromosome 11 open reading frame 21
C1ORF56 chromosome 1 open reading frame 56
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD8A CD8a molecule
CENPO centromere protein O
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHM choroideremia (Rab escort protein 1)
COPZ2 coatomer protein complex, subunit zeta 2
CPB2 carboxypeptidase B2 (plasma)
CRIP1 cysteine-rich protein 1 (intestinal)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXADR coxsackie virus and adenovirus receptor
DCAF4 DDB1 and CUL4 associated factor 4
DLK2 delta-like 2 homolog (Drosophila)
DNM3 dynamin 3
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EPHX2 epoxide hydrolase 2, cytoplasmic
EXOC5 exocyst complex component 5
FAM76A family with sequence similarity 76, member A
FBXL7 F-box and leucine-rich repeat protein 7
FOXI1 forkhead box I1
GATA4 GATA binding protein 4
GK3P glycerol kinase 3 pseudogene
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRPR gastrin-releasing peptide receptor
GTF2I general transcription factor IIi
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC11 histone deacetylase 11
HLA-J major histocompatibility complex, class I, J (pseudogene)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNIP1 Kv channel interacting protein 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCTD20 potassium channel tetramerization domain containing 20
KIAA1024 KIAA1024
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KRT83 keratin 83, type II
LATS1 large tumor suppressor kinase 1
LIN7A lin-7 homolog A (C. elegans)
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MOCS3 molybdenum cofactor synthesis 3
MTCP1 mature T-cell proliferation 1
MVP major vault protein
NIPAL2 NIPA-like domain containing 2
NPR3 natriuretic peptide receptor 3
NSUN6 NOP2/Sun domain family, member 6
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPAP2C phosphatidic acid phosphatase type 2C
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3D RAB3D, member RAS oncogene family
RCAN3 RCAN family member 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
SCD5 stearoyl-CoA desaturase 5
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK2 serum/glucocorticoid regulated kinase 2
SIRAL2 SIR2 antiphage like 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SNCAIP synuclein, alpha interacting protein
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
STAB2 stabilin 2
SYTL2 synaptotagmin-like 2
TFF2 trefoil factor 2
TMEM121 transmembrane protein 121
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULBP2 UL16 binding protein 2
VN1R1 vomeronasal 1 receptor 1
WDR33 WD repeat domain 33
ZNF230 zinc finger protein 230
ZSWIM1 zinc finger, SWIM-type containing 1