cartilage disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

153 genes co-occuring with the disease cartilage disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ANKH ANKH inorganic pyrophosphate transport regulator 2.08128
MATN1 matrilin 1, cartilage matrix protein 1.53128
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.43947
PPA1 pyrophosphatase (inorganic) 1 1.22345
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.20353
ACAN aggrecan 1.12614
ALPL alkaline phosphatase, liver/bone/kidney 1.11603
CRP C-reactive protein, pentraxin-related 1.10132
ALPPL2 alkaline phosphatase, placental-like 2 1.06522
ALPP alkaline phosphatase, placental 1.0648
IL1RN interleukin 1 receptor antagonist 1.00794
COMP cartilage oligomeric matrix protein 0.940364
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.836427
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.808949
PTH parathyroid hormone 0.794181
IL6R interleukin 6 receptor 0.786394
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.724502
COL2A1 collagen, type II, alpha 1 0.72329
COL10A1 collagen, type X, alpha 1 0.717232
SLC26A1 solute carrier family 26 (anion exchanger), member 1 0.699919
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.690694
PRTN3 proteinase 3 0.689893
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.683493
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.681894
HFE hemochromatosis 0.660008
NLRP3 NLR family, pyrin domain containing 3 0.646559
BBX bobby sox homolog (Drosophila) 0.636708
ST7 suppression of tumorigenicity 7 0.635528
SPTA1 spectrin, alpha, erythrocytic 1 0.59874
MMP3 matrix metallopeptidase 3 0.574994
MRAP melanocortin 2 receptor accessory protein 0.574217
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.57305
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.55712
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.55712
CLCNKB chloride channel, voltage-sensitive Kb 0.552075
PAX1 paired box 1 0.549747
HGD homogentisate 1,2-dioxygenase 0.535409
CD79A CD79a molecule, immunoglobulin-associated alpha 0.52536
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.494648
IVD isovaleryl-CoA dehydrogenase 0.491597
MGAM maltase-glucoamylase 0.486266
NELL1 NEL-like 1 (chicken) 0.47753
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.474119
TNF tumor necrosis factor 0.461639
TOLLIP toll interacting protein 0.459751
COL9A1 collagen, type IX, alpha 1 0.447687
TRIM47 tripartite motif containing 47 0.433772
IGHA1 immunoglobulin heavy constant alpha 1 0.430017
ADAM15 ADAM metallopeptidase domain 15 0.42364
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.418019
HIF3A hypoxia inducible factor 3, alpha subunit 0.417644
COL9A2 collagen, type IX, alpha 2 0.401199
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.394491
GPANK1 G patch domain and ankyrin repeats 1 0.391885
RUNX2 runt-related transcription factor 2 0.384822
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.379256
MGP matrix Gla protein 0.363347
HLA-C major histocompatibility complex, class I, C 0.361133
TGFB1 transforming growth factor, beta 1 0.357446
CXCL8 chemokine (C-X-C motif) ligand 8 0.346042
HSH2D hematopoietic SH2 domain containing 0.321545
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.319726
COL11A2 collagen, type XI, alpha 2 0.319726
ACVR1 activin A receptor, type I 0.31029
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.307757
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.301976
CASR calcium-sensing receptor 0.301615
C5ORF38 chromosome 5 open reading frame 38 0.292975
CCL4 chemokine (C-C motif) ligand 4 0.269043
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.264431
COL11A1 collagen, type XI, alpha 1 0.263722
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.259124
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.256652
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.253831
MRI1 methylthioribose-1-phosphate isomerase 1 0.251718
B2M beta-2-microglobulin 0.24996
IL6 interleukin 6 0.249608
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.243995
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.238054
CTSK cathepsin K 0.23666
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.235268
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.231448
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.231102
CLTC clathrin, heavy chain (Hc) 0.230755
MID2 midline 2 0.22937
BGLAP bone gamma-carboxyglutamate (gla) protein 0.227642
TREM1 triggering receptor expressed on myeloid cells 1 0.224884
KIAA0101 KIAA0101 0.217352
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.215992
IL1B interleukin 1, beta 0.204593
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.200656
SPP1 secreted phosphoprotein 1 0.195183
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.18621
HDAC4 histone deacetylase 4 0.182666
GUSB glucuronidase, beta 0.175146
SP7 Sp7 transcription factor 0.172544
MSX2 msh homeobox 2 0.170544
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.170054
CD4 CD4 molecule 0.158778
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.158605
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.138478
GGT2 gamma-glutamyltransferase 2 0.138198
VCAN versican 0.137996
LARS leucyl-tRNA synthetase 0.13699
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.136641
CCK cholecystokinin 0.136409
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.136368
ASPN asporin 0.135988
NCOA1 nuclear receptor coactivator 1 0.135301
GGT1 gamma-glutamyltransferase 1 0.131377
CD1D CD1d molecule 0.130712
ENO1 enolase 1, (alpha) 0.128918
HRH2 histamine receptor H2 0.127554
MSX1 msh homeobox 1 0.127329
KNTC1 kinetochore associated 1 0.127126
TF transferrin 0.126945
CD52 CD52 molecule 0.126868
TIMP1 TIMP metallopeptidase inhibitor 1 0.126524
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.126497
IL1R1 interleukin 1 receptor, type I 0.1262
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.126173
LCK LCK proto-oncogene, Src family tyrosine kinase 0.125757
IHH indian hedgehog 0.125329
IBSP integrin-binding sialoprotein 0.1253
CALR calreticulin 0.124432
FBN2 fibrillin 2 0.123744
RARS arginyl-tRNA synthetase 0.123712
CARD17 caspase recruitment domain family, member 17 0.123517
LAX1 lymphocyte transmembrane adaptor 1 0.123452
CD163 CD163 molecule 0.123223
IFNA2 interferon, alpha 2 0.122586
CALCA calcitonin-related polypeptide alpha 0.122064
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.121851
AMBP alpha-1-microglobulin/bikunin precursor 0.120864
PLA2G1B phospholipase A2, group IB (pancreas) 0.120563
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.119826
HIST1H4I histone cluster 1, H4i 0.119227
HIST1H4C histone cluster 1, H4c 0.119227
HIST1H4H histone cluster 1, H4h 0.119227
HIST1H4K histone cluster 1, H4k 0.119227
HIST2H4B histone cluster 2, H4b 0.119227
HIST1H4B histone cluster 1, H4b 0.119227
HIST1H4A histone cluster 1, H4a 0.119227
HIST1H4F histone cluster 1, H4f 0.119227
HIST1H4E histone cluster 1, H4e 0.119227
HIST1H4J histone cluster 1, H4j 0.119227
HIST1H4D histone cluster 1, H4d 0.119227
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.119186
CD68 CD68 molecule 0.119186
HIST2H4A histone cluster 2, H4a 0.119145
HIST1H4L histone cluster 1, H4l 0.118981
HIST4H4 histone cluster 4, H4 0.118939
DAXX death-domain associated protein 0.118145