cataract Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)|Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)|Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) (Experimental Factor Ontology, EFO_0001059)
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Genes

10 genes associated with the disease cataract in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
CRYGA crystallin, gamma A
CRYGB crystallin, gamma B
DMPK dystrophia myotonica-protein kinase
ERCC2 excision repair cross-complementation group 2
GJA8 gap junction protein, alpha 8, 50kDa
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
SLC16A12 solute carrier family 16, member 12
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1