cataracts Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)|Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)|Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) (Experimental Factor Ontology, EFO_0001059)
Similar Terms
Downloads & Tools

Genes

45 genes co-occuring with the biological term cataracts in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM9 ADAM metallopeptidase domain 9
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BEST1 bestrophin 1
BFSP1 beaded filament structural protein 1, filensin
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYBA1 crystallin, beta A1
CRYBB2 crystallin, beta B2
CRYBB3 crystallin, beta B3
CRYGB crystallin, gamma B
CRYGC crystallin, gamma C
CRYGD crystallin, gamma D
CRYGS crystallin, gamma S
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
EPHA2 EPH receptor A2
EZR ezrin
FAR1 fatty acyl CoA reductase 1
FTO fat mass and obesity associated
FYCO1 FYVE and coiled-coil domain containing 1
GALK1 galactokinase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJA3 gap junction protein, alpha 3, 46kDa
GJA8 gap junction protein, alpha 8, 50kDa
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HSF4 heat shock transcription factor 4
IFNGR1 interferon gamma receptor 1
JAM3 junctional adhesion molecule 3
KEAP1 kelch-like ECH-associated protein 1
KRT14 keratin 14, type I
LCA5 Leber congenital amaurosis 5
LIM2 lens intrinsic membrane protein 2, 19kDa
LTBP1 latent transforming growth factor beta binding protein 1
MIP major intrinsic protein of lens fiber
MIRLET7B microRNA let-7b
MSRB1 methionine sulfoxide reductase B1
MYH9 myosin, heavy chain 9, non-muscle
PAX6 paired box 6
PITX3 paired-like homeodomain 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TBC1D20 TBC1 domain family, member 20
XDH xanthine dehydrogenase