cathepsin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

209 genes co-occuring with the biological term cathepsin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACP5 acid phosphatase 5, tartrate resistant
ACTN1 actinin, alpha 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALPI alkaline phosphatase, intestinal
ANTXR2 anthrax toxin receptor 2
APP amyloid beta (A4) precursor protein
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP13A2 ATPase type 13A2
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
BACE1 beta-site APP-cleaving enzyme 1
BAX BCL2-associated X protein
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BLMH bleomycin hydrolase
BPI bactericidal/permeability-increasing protein
BRCA1 breast cancer 1, early onset
C5 complement component 5
C5AR1 complement component 5a receptor 1
CAPN1 calpain 1, (mu/I) large subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC91 coiled-coil domain containing 91
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CHN1 chimerin 1
CIITA class II, major histocompatibility complex, transactivator
CLU clusterin
COL1A1 collagen, type I, alpha 1
CORO1C coronin, actin binding protein, 1C
CREB1 cAMP responsive element binding protein 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CST5 cystatin D
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CTSA cathepsin A
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSE cathepsin E
CTSF cathepsin F
CTSG cathepsin G
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CTSW cathepsin W
CTSZ cathepsin Z
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DAPK1 death-associated protein kinase 1
DCD dermcidin
DRD2 dopamine receptor D2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELN elastin
ENO1 enolase 1, (alpha)
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FBLN1 fibulin 1
FBLN5 fibulin 5
FGF2 fibroblast growth factor 2 (basic)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLB1 galactosidase, beta 1
GNLY granulysin
GZMK granzyme K (granzyme 3; tryptase II)
HPSE heparanase
HPSE2 heparanase 2 (inactive)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HSPG2 heparan sulfate proteoglycan 2
HTT huntingtin
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
IRF1 interferon regulatory factor 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KNG1 kininogen 1
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
M6PR mannose-6-phosphate receptor (cation dependent)
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MCOLN1 mucolipin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO7A myosin VIIA
MZF1 myeloid zinc finger 1
NAPSA napsin A aspartic peptidase
NDRG1 N-myc downstream regulated 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NID1 nidogen 1
NLRP3 NLR family, pyrin domain containing 3
NME1 NME/NM23 nucleoside diphosphate kinase 1
NPY neuropeptide Y
NR1I3 nuclear receptor subfamily 1, group I, member 3
NTN1 netrin 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PENK proenkephalin
PFN1 profilin 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PLTP phospholipid transfer protein
PPARG peroxisome proliferator-activated receptor gamma
PRF1 perforin 1 (pore forming protein)
PRL prolactin
PRSS1 protease, serine, 1 (trypsin 1)
PRSS57 protease, serine, 57
PRTN3 proteinase 3
PSAP prosaposin
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
RAB27A RAB27A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RHOA ras homolog family member A
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RUNX1 runt-related transcription factor 1
S100P S100 calcium binding protein P
S100PBP S100P binding protein
SCPEP1 serine carboxypeptidase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SFTPC surfactant protein C
SHKBP1 SH3KBP1 binding protein 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLPI secretory leukocyte peptidase inhibitor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOST sclerostin
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPINK5 serine peptidase inhibitor, Kazal type 5
SPN sialophorin
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFE3 transcription factor binding to IGHM enhancer 3
TFRC transferrin receptor
TGM3 transglutaminase 3
TLR3 toll-like receptor 3
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase