cbfb_19800266_t_reg_lof_mouse_gpl1261_gds3577 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS3577
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Genes

127 genes differentially expressed following the cbfb_19800266_t_reg_lof_mouse_gpl1261_gds3577 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
SELO selenoprotein O 0.20384
LRRC48 leucine rich repeat containing 48 0.201927
RFX7 regulatory factor X, 7 0.192338
WDR17 WD repeat domain 17 0.188909
CCDC106 coiled-coil domain containing 106 0.185422
ZNF672 zinc finger protein 672 0.175587
SLC25A44 solute carrier family 25, member 44 0.171134
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.159942
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.157163
FAM219A family with sequence similarity 219, member A 0.152947
CTBP2 C-terminal binding protein 2 0.147607
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 0.137818
TUBB4B tubulin, beta 4B class IVb 0.13703
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.131765
CD151 CD151 molecule (Raph blood group) 0.124077
TMEM27 transmembrane protein 27 0.124077
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.121504
LHFPL4 lipoma HMGIC fusion partner-like 4 0.108622
TMEM72 transmembrane protein 72 0.097578
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.094896
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.091295
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.077339
ACSS2 acyl-CoA synthetase short-chain family member 2 0.077238
RSPO3 R-spondin 3 0.076422
ZPBP zona pellucida binding protein 0.068419
LAMA4 laminin, alpha 4 0.061666
PTRF polymerase I and transcript release factor 0.060764
FAM163B family with sequence similarity 163, member B 0.059347
GJC3 gap junction protein, gamma 3, 30.2kDa 0.057558
HOXA10 homeobox A10 0.055685
HUS1 HUS1 checkpoint homolog (S. pombe) 0.034825
TSPAN4 tetraspanin 4 0.03324
PSME4 proteasome (prosome, macropain) activator subunit 4 0.032563
NEURL1 neuralized E3 ubiquitin protein ligase 1 0.013032

decreased expression

Symbol Name Standardized Value
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -1.33689
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 -1.32463
TMEM150A transmembrane protein 150A -1.31195
SRBD1 S1 RNA binding domain 1 -1.30834
CSNK1A1 casein kinase 1, alpha 1 -1.28996
OAZ1 ornithine decarboxylase antizyme 1 -1.2791
THBS1 thrombospondin 1 -1.2616
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.2586
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -1.18413
NCAM1 neural cell adhesion molecule 1 -1.15711
KIAA1407 KIAA1407 -1.13069
VAV3 vav 3 guanine nucleotide exchange factor -1.10451
GAS7 growth arrest-specific 7 -1.06671
MEX3C mex-3 RNA binding family member C -1.05095
BCL10 B-cell CLL/lymphoma 10 -0.997827
LHX6 LIM homeobox 6 -0.993143
ST7L suppression of tumorigenicity 7 like -0.900466
PAIP1 poly(A) binding protein interacting protein 1 -0.869029
TMEM218 transmembrane protein 218 -0.867456
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.846695
DGKB diacylglycerol kinase, beta 90kDa -0.842532
ZBTB10 zinc finger and BTB domain containing 10 -0.832684
AGBL3 ATP/GTP binding protein-like 3 -0.832531
ANXA13 annexin A13 -0.832531
PHF20 PHD finger protein 20 -0.815804
HRH4 histamine receptor H4 -0.802089
MGA MGA, MAX dimerization protein -0.800175
XK X-linked Kx blood group -0.781964
EBNA1BP2 EBNA1 binding protein 2 -0.768248
BMP8B bone morphogenetic protein 8b -0.758854
KLHDC3 kelch domain containing 3 -0.754663
SEBOX SEBOX homeobox -0.750812
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -0.74631
FGF3 fibroblast growth factor 3 -0.74631
C16ORF90 chromosome 16 open reading frame 90 -0.7408
PALLD palladin, cytoskeletal associated protein -0.734651
XPO4 exportin 4 -0.717756
NHEJ1 nonhomologous end-joining factor 1 -0.706501
PRRX1 paired related homeobox 1 -0.685489
GATA6 GATA binding protein 6 -0.685305
PRSS2 protease, serine, 2 (trypsin 2) -0.677194
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.653708
SPG20 spastic paraplegia 20 (Troyer syndrome) -0.653182
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.642302
CD109 CD109 molecule -0.639258
RNF220 ring finger protein 220 -0.631906
SESN3 sestrin 3 -0.626092
ERI3 ERI1 exoribonuclease family member 3 -0.623404
GPR162 G protein-coupled receptor 162 -0.62046
KDM2B lysine (K)-specific demethylase 2B -0.618484
DYM dymeclin -0.614986
METAP1 methionyl aminopeptidase 1 -0.601805
STEAP2 STEAP family member 2, metalloreductase -0.600527
SERP2 stress-associated endoplasmic reticulum protein family member 2 -0.587831
DNAAF5 dynein, axonemal, assembly factor 5 -0.583274
HAPLN1 hyaluronan and proteoglycan link protein 1 -0.581299
MMP2 matrix metallopeptidase 2 -0.579869
AQP5 aquaporin 5 -0.571258
WWC1 WW and C2 domain containing 1 -0.559315
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -0.558984
DPH1 diphthamide biosynthesis 1 -0.547851
PBX4 pre-B-cell leukemia homeobox 4 -0.542805
RAB6A RAB6A, member RAS oncogene family -0.542034
GRIK4 glutamate receptor, ionotropic, kainate 4 -0.524554
CDKL4 cyclin-dependent kinase-like 4 -0.510797
KCTD15 potassium channel tetramerization domain containing 15 -0.504298
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) -0.497665
EFTUD1 elongation factor Tu GTP binding domain containing 1 -0.494113
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -0.486722
ADRA2A adrenoceptor alpha 2A -0.476011
LMNA lamin A/C -0.472331
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.468175
ASCL1 achaete-scute family bHLH transcription factor 1 -0.464478
GRM2 glutamate receptor, metabotropic 2 -0.455764
EIF3F eukaryotic translation initiation factor 3, subunit F -0.455342
ELMOD3 ELMO/CED-12 domain containing 3 -0.454563
SSC5D scavenger receptor cysteine rich family, 5 domains -0.43851
FAM110B family with sequence similarity 110, member B -0.43771
KAZN kazrin, periplakin interacting protein -0.437441
LRRC8E leucine rich repeat containing 8 family, member E -0.066889
TRIM9 tripartite motif containing 9 -0.066248
TM7SF3 transmembrane 7 superfamily member 3 -0.060935
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.052182
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -0.042842
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.040608
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.037723
PWWP2A PWWP domain containing 2A -0.03679
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 -0.03106
CRABP2 cellular retinoic acid binding protein 2 -0.022598
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.017705
PTPRK protein tyrosine phosphatase, receptor type, K -0.013031
TRIM68 tripartite motif containing 68 -0.008996
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.008722