ccl27 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description chemokine (C-C motif) ligand 27|This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 10850)
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Genes

19 genes co-occuring with the biological term ccl27 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CCL17 chemokine (C-C motif) ligand 17
CCL20 chemokine (C-C motif) ligand 20
CCL22 chemokine (C-C motif) ligand 22
CCL27 chemokine (C-C motif) ligand 27
CCL28 chemokine (C-C motif) ligand 28
CCR10 chemokine (C-C motif) receptor 10
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL18 interleukin 18
IL1A interleukin 1, alpha
MAPK14 mitogen-activated protein kinase 14
PDPN podoplanin
SELPLG selectin P ligand
TNF tumor necrosis factor