cd27 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description CD27 molecule|The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 939)
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Genes

24 genes co-occuring with the biological term cd27 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD24 CD24 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CXCR3 chemokine (C-X-C motif) receptor 3
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
IL2 interleukin 2
IL4 interleukin 4
IL7 interleukin 7
NGFR nerve growth factor receptor
PDCD1 programmed cell death 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PMP22 peripheral myelin protein 22
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIVA1 SIVA1, apoptosis-inducing factor
SYK spleen tyrosine kinase
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53