cd28 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description CD28 molecule|The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 940)
Similar Terms
Downloads & Tools

Genes

72 genes co-occuring with the biological term cd28 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCL2L1 BCL2-like 1
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CD160 CD160 molecule
CD2 CD2 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD40LG CD40 ligand
CD5 CD5 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD99 CD99 molecule
CDC42 cell division cycle 42
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DPP4 dipeptidyl-peptidase 4
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FLNA filamin A, alpha
FOXP3 forkhead box P3
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HAVCR1 hepatitis A virus cellular receptor 1
HK2 hexokinase 2
HSH2D hematopoietic SH2 domain containing
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL2 interleukin 2
IL21 interleukin 21
IL23R interleukin 23 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITK IL2-inducible T-cell kinase
JUN jun proto-oncogene
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NFAM1 NFAT activating protein with ITAM motif 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDCD1 programmed cell death 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
STK10 serine/threonine kinase 10
TNF tumor necrosis factor
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
VAV1 vav 1 guanine nucleotide exchange factor
XCL1 chemokine (C motif) ligand 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa