cd81 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description CD81 molecule|The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 975)
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Genes

37 genes co-occuring with the biological term cd81 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCAP31 B-cell receptor-associated protein 31
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD19 CD19 molecule
CD28 CD28 molecule
CD44 CD44 molecule (Indian blood group)
CD63 CD63 molecule
CD81 CD81 molecule
CD82 CD82 molecule
CD9 CD9 molecule
CLDN1 claudin 1
CLDN6 claudin 6
CLDN9 claudin 9
CLEC4M C-type lectin domain family 4, member M
CXCL8 chemokine (C-X-C motif) ligand 8
EGFR epidermal growth factor receptor
EZR ezrin
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
IGSF8 immunoglobulin superfamily, member 8
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LCK LCK proto-oncogene, Src family tyrosine kinase
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSN moesin
OCLN occludin
PRKCB protein kinase C, beta
PRNP prion protein
PTGFRN prostaglandin F2 receptor inhibitor
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RDX radixin
SCARB1 scavenger receptor class B, member 1
SDC2 syndecan 2
TFRC transferrin receptor
VCAM1 vascular cell adhesion molecule 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon