cd95 death-inducing signaling complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. (Gene Ontology, GO_0031265)
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6 proteins localized to the cd95 death-inducing signaling complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FADD Fas (TNFRSF6)-associated via death domain 0.663342
FAF1 Fas (TNFRSF6) associated factor 1 0.663342
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.663342
FAS Fas cell surface death receptor 0.663342
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.663342
CFLAR CASP8 and FADD-like apoptosis regulator 0.03318