cdc25c Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description cell division cycle 25C|This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 995)
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Genes

33 genes co-occuring with the biological term cdc25c in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND3 cyclin D3
CCNE1 cyclin E1
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CSNK2A1 casein kinase 2, alpha 1 polypeptide
EPHB2 EPH receptor B2
FLNA filamin A, alpha
FOXM1 forkhead box M1
KIF22 kinesin family member 22
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGR progesterone receptor
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKN1 protein kinase N1
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
SNRPE small nuclear ribonucleoprotein polypeptide E
TP53 tumor protein p53
TP63 tumor protein p63
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma