cdk1 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description cyclin-dependent kinase 1|The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 983)
Similar Terms
Downloads & Tools

Genes

117 proteins co-occuring with the biological term cdk1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC1 anaphase promoting complex subunit 1
AR androgen receptor
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCLAF1 BCL2-associated transcription factor 1
BRCA1 breast cancer 1, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CASP8 caspase 8, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC6 cell division cycle 6
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLASP2 cytoplasmic linker associated protein 2
CREM cAMP responsive element modulator
CUEDC2 CUE domain containing 2
CUX1 cut-like homeobox 1
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DCTN6 dynactin 6
DLG1 discs, large homolog 1 (Drosophila)
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
ECT2 epithelial cell transforming 2
ELAVL1 ELAV like RNA binding protein 1
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FLNA filamin A, alpha
FOXM1 forkhead box M1
FOXO1 forkhead box O1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GOLGA2 golgin A2
GORASP1 golgi reassembly stacking protein 1, 65kDa
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
INCENP inner centromere protein antigens 135/155kDa
ING1 inhibitor of growth family, member 1
KAT7 K(lysine) acetyltransferase 7
KIF11 kinesin family member 11
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK6 mitogen-activated protein kinase 6
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MPLKIP M-phase specific PLK1 interacting protein
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYOD1 myogenic differentiation 1
NBN nibrin
NCAPD3 non-SMC condensin II complex, subunit D3
NCOA3 nuclear receptor coactivator 3
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK9 NIMA-related kinase 9
NIFK nucleolar protein interacting with the FHA domain of MKI67
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCLEOLIN nucleolin multifunctional protein
NUMA1 nuclear mitotic apparatus protein 1
NUP98 nucleoporin 98kDa
NUSAP1 nucleolar and spindle associated protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRC1 protein regulator of cytokinesis 1
PSRC1 proline/serine-rich coiled-coil 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RTN4 reticulon 4
RUNX1 runt-related transcription factor 1
SAMHD1 SAM domain and HD domain 1
SLBP stem-loop binding protein
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TACC3 transforming, acidic coiled-coil containing protein 3
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TUBB tubulin, beta class I
TUBGCP6 tubulin, gamma complex associated protein 6
UBE2I ubiquitin-conjugating enzyme E2I
UIMC1 ubiquitin interaction motif containing 1
USP1 ubiquitin specific peptidase 1
VIM vimentin
WEE1 WEE1 G2 checkpoint kinase
WEE2 WEE1 homolog 2 (S. pombe)
WWC1 WW and C2 domain containing 1
XPO1 exportin 1