cdk5 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description cyclin-dependent kinase 5|This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] (NCBI Entrez Gene Database, 1020)
Similar Terms
Downloads & Tools

Genes

118 proteins co-occuring with the biological term cdk5 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ADD2 adducin 2 (beta)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMPH amphiphysin
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATM ATM serine/threonine kinase
AXIN1 axin 1
BCL2 B-cell CLL/lymphoma 2
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CDK16 cyclin-dependent kinase 16
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CORO1A coronin, actin binding protein, 1A
CRMP1 collapsin response mediator protein 1
CSNK1E casein kinase 1, epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND2 catenin (cadherin-associated protein), delta 2
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBN1 drebrin 1
DCX doublecortin
DIXDC1 DIX domain containing 1
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNM1 dynamin 1
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
ELAVL1 ELAV like RNA binding protein 1
EPRS glutamyl-prolyl-tRNA synthetase
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESYT1 extended synaptotagmin-like protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HDAC5 histone deacetylase 5
HMGB1 high mobility group box 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
IRS1 insulin receptor substrate 1
KALRN kalirin, RhoGEF kinase
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF13B kinesin family member 13B
LMTK1 lemur tail kinase 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MEF2A myocyte enhancer factor 2A
MEF2D myocyte enhancer factor 2D
MSN moesin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ODF1 outer dense fiber of sperm tails 1
OPRD1 opioid receptor, delta 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PHACTR3 phosphatase and actin regulator 3
PLD2 phospholipase D2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRDX2 peroxiredoxin 2
PTK2 protein tyrosine kinase 2
PXN paxillin
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RB1 retinoblastoma 1
RHOQ ras homolog family member Q
RPL13A ribosomal protein L13a
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMAD2 SMAD family member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
STMN3 stathmin-like 3
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SYN1 synapsin I
SYNJ1 synaptojanin 1
TH tyrosine hydroxylase
TIAM1 T-cell lymphoma invasion and metastasis 1
TLN1 talin 1
TP53 tumor protein p53
TPPP tubulin polymerization promoting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VIM vimentin
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2