cdx2_21402776_jejunum_epithelium_lof_mouse_gpl11044_gse24633 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE24633
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Genes

116 genes differentially expressed following the cdx2_21402776_jejunum_epithelium_lof_mouse_gpl11044_gse24633 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
HEXA hexosaminidase A (alpha polypeptide) 2.81687
DNASE1 deoxyribonuclease I 2.62958
TNK2 tyrosine kinase, non-receptor, 2 1.98897
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.98897
REG3A regenerating islet-derived 3 alpha 1.52143
GML glycosylphosphatidylinositol anchored molecule like 1.52143
OAT ornithine aminotransferase 1.52143
GSTA4 glutathione S-transferase alpha 4 1.52143
CTSE cathepsin E 1.52143
NT5C3A 5'-nucleotidase, cytosolic IIIA 1.52143
LY6D lymphocyte antigen 6 complex, locus D 1.52143
PRSS30P protease, serine, 30, pseudogene 1.52143
MTCH2 mitochondrial carrier 2 1.52143
RBP1 retinol binding protein 1, cellular 1.34794
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.29978
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.29978
INSM1 insulinoma-associated 1 1.29978
RNASE4 ribonuclease, RNase A family, 4 1.22281
MRC1 mannose receptor, C type 1 1.22281
TST thiosulfate sulfurtransferase (rhodanese) 1.21855
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.15418
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.15418
BIN1 bridging integrator 1 1.15418
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.15418
MMD monocyte to macrophage differentiation-associated 1.15418
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.14485
FAAH fatty acid amide hydrolase 1.12632
ANGPTL4 angiopoietin-like 4 1.12632
NDRG1 N-myc downstream regulated 1 1.12632
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 1.12632
TLE3 transducin-like enhancer of split 3 1.12632
NAGA N-acetylgalactosaminidase, alpha- 1.12632
GJB1 gap junction protein, beta 1, 32kDa 1.08048
BACE2 beta-site APP-cleaving enzyme 2 1.06574
DERL1 derlin 1 1.01116
NEK7 NIMA-related kinase 7 0.983129
YAF2 YY1 associated factor 2 0.969901
VSIG2 V-set and immunoglobulin domain containing 2 0.908507
FUT2 fucosyltransferase 2 (secretor status included) 0.497628
PEPD peptidase D 0.497628
LGMN legumain 0.497628
RHOB ras homolog family member B 0.497628
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.497628
WSB1 WD repeat and SOCS box containing 1 0.497628
EDN2 endothelin 2 0.449753
TK2 thymidine kinase 2, mitochondrial 0.440866
TMIGD1 transmembrane and immunoglobulin domain containing 1 0.407571
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.350516
LAMB3 laminin, beta 3 0.305171
CA2 carbonic anhydrase II 0.303441
MCOLN2 mucolipin 2 0.265705
PTGR1 prostaglandin reductase 1 0.256661
CAPN5 calpain 5 0.255475
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.201084
CD164 CD164 molecule, sialomucin 0.073177
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.073177
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 0.040427
VIL1 villin 1 0.01723
DEGS1 delta(4)-desaturase, sphingolipid 1 0.012924
HGFAC HGF activator 0.012924
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0.012924

decreased expression

Symbol Name Standardized Value
SQLE squalene epoxidase -0.362732
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -0.355959
PPARG peroxisome proliferator-activated receptor gamma -0.351041
DYNLT3 dynein, light chain, Tctex-type 3 -0.351041
MYL7 myosin, light chain 7, regulatory -0.344231
PMP22 peripheral myelin protein 22 -0.321381
MEA1 male-enhanced antigen 1 -0.309713
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.309713
MEFV Mediterranean fever -0.302426
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.296895
RWDD2B RWD domain containing 2B -0.29449
SPHK2 sphingosine kinase 2 -0.29449
PLCD1 phospholipase C, delta 1 -0.29449
GADD45B growth arrest and DNA-damage-inducible, beta -0.29449
CTNS cystinosin, lysosomal cystine transporter -0.275855
STARD5 StAR-related lipid transfer (START) domain containing 5 -0.274887
USP18 ubiquitin specific peptidase 18 -0.271495
FAM114A1 family with sequence similarity 114, member A1 -0.260914
F10 coagulation factor X -0.253402
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.253402
CTSC cathepsin C -0.249229
EPCAM epithelial cell adhesion molecule -0.249229
PLD3 phospholipase D family, member 3 -0.249229
HADH hydroxyacyl-CoA dehydrogenase -0.249229
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -0.247225
LTK leukocyte receptor tyrosine kinase -0.235486
GPX1 glutathione peroxidase 1 -0.235486
CPD carboxypeptidase D -0.235486
BTC betacellulin -0.235486
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -0.235486
KRT23 keratin 23, type I -0.235486
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.235486
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.231487
GIP gastric inhibitory polypeptide -0.202427
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -0.202427
POMP proteasome maturation protein -0.196171
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -0.196171
AS3MT arsenite methyltransferase -0.196171
STARD10 StAR-related lipid transfer (START) domain containing 10 -0.193547
GRTP1 growth hormone regulated TBC protein 1 -0.179449
PANX1 pannexin 1 -0.154726
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -0.153363
GAS6 growth arrest-specific 6 -0.144177
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.136339
CFI complement factor I -0.129818
NR0B2 nuclear receptor subfamily 0, group B, member 2 -0.129818
LZTR1 leucine-zipper-like transcription regulator 1 -0.128296
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.12395
HPN hepsin -0.114878
FXYD3 FXYD domain containing ion transport regulator 3 -0.113551
COPS2 COP9 signalosome subunit 2 -0.097644
LTA4H leukotriene A4 hydrolase -0.075638
SNURF SNRPN upstream reading frame -0.075638
SNRPN small nuclear ribonucleoprotein polypeptide N -0.075638
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.058665