cebpa Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description CCAAT/enhancer binding protein (C/EBP), alpha|This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 1050)
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Genes

40 genes co-occuring with the biological term cebpa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ASXL1 additional sex combs like transcriptional regulator 1
BAALC brain and acute leukemia, cytoplasmic
BCL2 B-cell CLL/lymphoma 2
CALR calreticulin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD33 CD33 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CORO1A coronin, actin binding protein, 1A
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FABP1 fatty acid binding protein 1, liver
FLT3 fms-related tyrosine kinase 3
GATA2 GATA binding protein 2
HK3 hexokinase 3 (white cell)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KAT5 K(lysine) acetyltransferase 5
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
MAPK7 mitogen-activated protein kinase 7
MIR124-1 microRNA 124-1
MIR181A1 microRNA 181a-1
MIR29B1 microRNA 29b-1
MIRLET7A3 microRNA let-7a-3
MN1 meningioma (disrupted in balanced translocation) 1
MPO myeloperoxidase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PDIA2 protein disulfide isomerase family A, member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX4 SRY (sex determining region Y)-box 4
SPI1 Spi-1 proto-oncogene
TET2 tet methylcytosine dioxygenase 2
YY1 YY1 transcription factor