cefadroxil-1323 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cefadroxil-1323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ASB8 ankyrin repeat and SOCS box containing 8
ASGR2 asialoglycoprotein receptor 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF5 activating transcription factor 5
ATG9A autophagy related 9A
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN2L ataxin 2-like
BAHCC1 BAH domain and coiled-coil containing 1
BAK1 BCL2-antagonist/killer 1
CA1 carbonic anhydrase I
CAPN15 calpain 15
CENPT centromere protein T
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRY2 cryptochrome circadian clock 2
DCTN1 dynactin 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLG4 discs, large homolog 4 (Drosophila)
DPEP2 dipeptidase 2
ELOVL5 ELOVL fatty acid elongase 5
EVA1B eva-1 homolog B (C. elegans)
EXOSC2 exosome component 2
EXT1 exostosin glycosyltransferase 1
FAM3A family with sequence similarity 3, member A
FBXL18 F-box and leucine-rich repeat protein 18
GOLIM4 golgi integral membrane protein 4
GRB10 growth factor receptor-bound protein 10
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
IFI16 interferon, gamma-inducible protein 16
IL1R2 interleukin 1 receptor, type II
ITGB5 integrin, beta 5
JMJD4 jumonji domain containing 4
KHSRP KH-type splicing regulatory protein
LDB1 LIM domain binding 1
LOC100272216 uncharacterized LOC100272216
LPPR3 lipid phosphate phosphatase-related protein type 3
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK7 mitogen-activated protein kinase 7
MARK2 MAP/microtubule affinity-regulating kinase 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYT1 myelin transcription factor 1
NLRP1 NLR family, pyrin domain containing 1
NTSR1 neurotensin receptor 1 (high affinity)
NUCB1 nucleobindin 1
OGFR opioid growth factor receptor
ORAI2 ORAI calcium release-activated calcium modulator 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAPOLG poly(A) polymerase gamma
PBX2 pre-B-cell leukemia homeobox 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELP1 proline, glutamate and leucine rich protein 1
PEX6 peroxisomal biogenesis factor 6
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCSH protein kinase C substrate 80K-H
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB5C RAB5C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM42 RNA binding motif protein 42
RUNX3 runt-related transcription factor 3
SCAMP4 secretory carrier membrane protein 4
SEC23IP SEC23 interacting protein
SFXN3 sideroflexin 3
SIPA1 signal-induced proliferation-associated 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPATA2L spermatogenesis associated 2-like
SPN sialophorin
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK11 serine/threonine kinase 11
SUGP2 SURP and G patch domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SURF1 surfeit 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCOF1 Treacher Collins-Franceschetti syndrome 1
TFEB transcription factor EB
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOB2 transducer of ERBB2, 2
TPCN1 two pore segment channel 1
TRIM14 tripartite motif containing 14
TUBB3 tubulin, beta 3 class III
USF2 upstream transcription factor 2, c-fos interacting
WDR62 WD repeat domain 62
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZER1 zyg-11 related, cell cycle regulator
ZMYND8 zinc finger, MYND-type containing 8
ZNF324 zinc finger protein 324
ZNF580 zinc finger protein 580
ZNF609 zinc finger protein 609
ZNF667 zinc finger protein 667
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD3 abhydrolase domain containing 3
ACPP acid phosphatase, prostate
ADAM10 ADAM metallopeptidase domain 10
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPS alkylglycerone phosphate synthase
AIDA axin interactor, dorsalization associated
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARMC6 armadillo repeat containing 6
ATAD2 ATPase family, AAA domain containing 2
ATP8B4 ATPase, class I, type 8B, member 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAX BCL2-associated X protein
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF30 chromosome 11 open reading frame 30
C1ORF109 chromosome 1 open reading frame 109
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CA2 carbonic anhydrase II
CAPRIN1 cell cycle associated protein 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDA1 DET1 and DDB1 associated 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHRS7B dehydrogenase/reductase (SDR family) member 7B
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCH1 GTP cyclohydrolase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GOLGA8B golgin A8 family, member B
GSR glutathione reductase
GTF2I general transcription factor IIi
GUF1 GUF1 GTPase homolog (S. cerevisiae)
H2BFS H2B histone family, member S (pseudogene)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HMGB3P1 high mobility group box 3 pseudogene 1
HP1BP3 heterochromatin protein 1, binding protein 3
IMPAD1 inositol monophosphatase domain containing 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KDM7A lysine (K)-specific demethylase 7A
KLHL12 kelch-like family member 12
LAMP5 lysosomal-associated membrane protein family, member 5
LIG4 ligase IV, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LPAR6 lysophosphatidic acid receptor 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MRPL42 mitochondrial ribosomal protein L42
MTMR11 myotubularin related protein 11
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NARFL nuclear prelamin A recognition factor-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NMD3 NMD3 ribosome export adaptor
NNT nicotinamide nucleotide transhydrogenase
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PGM3 phosphoglucomutase 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSAT1 phosphoserine aminotransferase 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RFX7 regulatory factor X, 7
RGS13 regulator of G-protein signaling 13
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF141 ring finger protein 141
RNF146 ring finger protein 146
SAMD9 sterile alpha motif domain containing 9
SELT selenoprotein T
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SETD8 SET domain containing (lysine methyltransferase) 8
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A40 solute carrier family 25, member 40
SRD5A3 steroid 5 alpha-reductase 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM14A transmembrane protein 14A
TMEM230 transmembrane protein 230
TRIM25 tripartite motif containing 25
YAF2 YY1 associated factor 2
YIPF5 Yip1 domain family, member 5
ZBTB6 zinc finger and BTB domain containing 6
ZNF227 zinc finger protein 227
ZNF350 zinc finger protein 350
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665
ZW10 zw10 kinetochore protein