cefadroxil-3259 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefadroxil-3259 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACVR1B activin A receptor, type IB
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARNT aryl hydrocarbon receptor nuclear translocator
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG13 autophagy related 13
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
C2ORF27A chromosome 2 open reading frame 27A
CDC25C cell division cycle 25C
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN17 claudin 17
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNASE1 deoxyribonuclease I
DTNA dystrobrevin, alpha
ELP6 elongator acetyltransferase complex subunit 6
ERAP1 endoplasmic reticulum aminopeptidase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO31 F-box protein 31
FH fumarate hydratase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR137 G protein-coupled receptor 137
HCAR3 hydroxycarboxylic acid receptor 3
HEG1 heart development protein with EGF-like domains 1
HHLA3 HERV-H LTR-associating 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT54 intraflagellar transport 54
IL17RC interleukin 17 receptor C
IL1A interleukin 1, alpha
INA internexin neuronal intermediate filament protein, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITSN1 intersectin 1 (SH3 domain protein)
KAT6A K(lysine) acetyltransferase 6A
KCTD2 potassium channel tetramerization domain containing 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHL24 kelch-like family member 24
KYNU kynureninase
MAST2 microtubule associated serine/threonine kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MEIS2 Meis homeobox 2
MFAP3 microfibrillar-associated protein 3
MSRB2 methionine sulfoxide reductase B2
MST1L macrophage stimulating 1-like
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO1B myosin IB
MYOF myoferlin
NECAB2 N-terminal EF-hand calcium binding protein 2
NF1 neurofibromin 1
NUMA1 nuclear mitotic apparatus protein 1
NYNRIN NYN domain and retroviral integrase containing
PARD6B par-6 family cell polarity regulator beta
PCDHGB5 protocadherin gamma subfamily B, 5
PDE4C phosphodiesterase 4C, cAMP-specific
PHC3 polyhomeotic homolog 3 (Drosophila)
PLCD1 phospholipase C, delta 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKD3 protein kinase D3
RAD52 RAD52 homolog (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
RIMS3 regulating synaptic membrane exocytosis 3
RIN2 Ras and Rab interactor 2
RIN3 Ras and Rab interactor 3
RNF39 ring finger protein 39
RYR2 ryanodine receptor 2 (cardiac)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIAH1 siah E3 ubiquitin protein ligase 1
SKI SKI proto-oncogene
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SPINK5 serine peptidase inhibitor, Kazal type 5
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF7 serine/arginine-rich splicing factor 7
SZT2 seizure threshold 2 homolog (mouse)
TAOK2 TAO kinase 2
TOP3A topoisomerase (DNA) III alpha
TRIO trio Rho guanine nucleotide exchange factor
TYRP1 tyrosinase-related protein 1
UBOX5 U-box domain containing 5
ZNF137P zinc finger protein 137, pseudogene
ZNF318 zinc finger protein 318
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAP2 ArfGAP with dual PH domains 2
ALS2CL ALS2 C-terminal like
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ATP13A2 ATPase type 13A2
AUTS2 autism susceptibility candidate 2
B9D2 B9 protein domain 2
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CAPRIN2 caprin family member 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CDC73 cell division cycle 73
CGREF1 cell growth regulator with EF-hand domain 1
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
COL4A5 collagen, type IV, alpha 5
CPTP ceramide-1-phosphate transfer protein
CSF1R colony stimulating factor 1 receptor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FAM114A2 family with sequence similarity 114, member A2
FBXL2 F-box and leucine-rich repeat protein 2
GCA grancalcin, EF-hand calcium binding protein
GMIP GEM interacting protein
GPR27 G protein-coupled receptor 27
GRTP1 growth hormone regulated TBC protein 1
GSTT1 glutathione S-transferase theta 1
HDAC4 histone deacetylase 4
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HPN hepsin
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYI hydroxypyruvate isomerase (putative)
IRF6 interferon regulatory factor 6
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC61 leucine rich repeat containing 61
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDRG4 NDRG family member 4
NOD1 nucleotide-binding oligomerization domain containing 1
NOL6 nucleolar protein 6 (RNA-associated)
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX1 neuronal pentraxin I
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
OVOL1 ovo-like zinc finger 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLH polymerase (DNA directed), eta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRAMEF11 PRAME family member 11
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHBDD3 rhomboid domain containing 3
RIN1 Ras and Rab interactor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SETD1A SET domain containing 1A
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAI2 snail family zinc finger 2
SPAG7 sperm associated antigen 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAOK1 TAO kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMEM180 transmembrane protein 180
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VEGFC vascular endothelial growth factor C
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
XK X-linked Kx blood group
ZBTB44 zinc finger and BTB domain containing 44
ZNF205 zinc finger protein 205
ZNF35 zinc finger protein 35
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696
ZNF701 zinc finger protein 701