| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the cefalexin-1273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AEN | apoptosis enhancing nuclease |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOL2 | apolipoprotein L, 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAD | BCL2-associated agonist of cell death |
| BCORL1 | BCL6 corepressor-like 1 |
| C1RL | complement component 1, r subcomponent-like |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CDC14A | cell division cycle 14A |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHMP6 | charged multivesicular body protein 6 |
| COL11A2 | collagen, type XI, alpha 2 |
| CTAGE5 | CTAGE family, member 5 |
| CYB561 | cytochrome b561 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DLG4 | discs, large homolog 4 (Drosophila) |
| ECSIT | ECSIT signalling integrator |
| EGR1 | early growth response 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| FAM127B | family with sequence similarity 127, member B |
| FLT1 | fms-related tyrosine kinase 1 |
| FST | follistatin |
| FUS | FUS RNA binding protein |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GPR107 | G protein-coupled receptor 107 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1E | histone cluster 1, H1e |
| HK2 | hexokinase 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| ICAM1 | intercellular adhesion molecule 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INHBA | inhibin, beta A |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAP4 | microtubule-associated protein 4 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAPOLA | poly(A) polymerase alpha |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PLSCR3 | phospholipid scramblase 3 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PORCN | porcupine homolog (Drosophila) |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTAFR | platelet-activating factor receptor |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RANBP1 | RAN binding protein 1 |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RPL7 | ribosomal protein L7 |
| RRP1B | ribosomal RNA processing 1B |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SIN3B | SIN3 transcription regulator family member B |
| SIRT5 | sirtuin 5 |
| SKIL | SKI-like proto-oncogene |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNHG20 | small nucleolar RNA host gene 20 |
| STX1A | syntaxin 1A (brain) |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNJ2 | synaptojanin 2 |
| TAOK1 | TAO kinase 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCF3 | transcription factor 3 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAM2 | translocation associated membrane protein 2 |
| TUBB3 | tubulin, beta 3 class III |
| TYMP | thymidine phosphorylase |
| UNC45A | unc-45 homolog A (C. elegans) |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF500 | zinc finger protein 500 |
| ZNF552 | zinc finger protein 552 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACOT13 | acyl-CoA thioesterase 13 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AIDA | axin interactor, dorsalization associated |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| AKTIP | AKT interacting protein |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| APIP | APAF1 interacting protein |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBS10 | Bardet-Biedl syndrome 10 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BTBD3 | BTB (POZ) domain containing 3 |
| C5 | complement component 5 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CASD1 | CAS1 domain containing 1 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CDC37L1 | cell division cycle 37-like 1 |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CLDND1 | claudin domain containing 1 |
| COMMD10 | COMM domain containing 10 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CTPS2 | CTP synthase 2 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial |
| DENND4A | DENN/MADD domain containing 4A |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DPY19L4 | dpy-19-like 4 (C. elegans) |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EGR2 | early growth response 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM222B | family with sequence similarity 222, member B |
| FHL3 | four and a half LIM domains 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LMAN1 | lectin, mannose-binding, 1 |
| MANEA | mannosidase, endo-alpha |
| MANSC1 | MANSC domain containing 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NFS1 | NFS1 cysteine desulfurase |
| NMD3 | NMD3 ribosome export adaptor |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PITRM1 | pitrilysin metallopeptidase 1 |
| POGK | pogo transposable element with KRAB domain |
| PRAF2 | PRA1 domain family, member 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RBM7 | RNA binding motif protein 7 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPE | ribulose-5-phosphate-3-epimerase |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SELT | selenoprotein T |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SIRT2 | sirtuin 2 |
| SLC25A46 | solute carrier family 25, member 46 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STBD1 | starch binding domain 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THEM6 | thioesterase superfamily member 6 |
| TLR4 | toll-like receptor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM16 | tripartite motif containing 16 |
| UBFD1 | ubiquitin family domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR5B | WD repeat domain 5B |
| YIPF5 | Yip1 domain family, member 5 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF227 | zinc finger protein 227 |
| ZNF250 | zinc finger protein 250 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF586 | zinc finger protein 586 |
| ZNF665 | zinc finger protein 665 |