cefalexin-1273 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the cefalexin-1273 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACTA2 actin, alpha 2, smooth muscle, aorta
AEN apoptosis enhancing nuclease
AKAP13 A kinase (PRKA) anchor protein 13
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOL2 apolipoprotein L, 2
ARHGAP35 Rho GTPase activating protein 35
ARNT aryl hydrocarbon receptor nuclear translocator
BAD BCL2-associated agonist of cell death
BCORL1 BCL6 corepressor-like 1
C1RL complement component 1, r subcomponent-like
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCND1 cyclin D1
CCNF cyclin F
CDC14A cell division cycle 14A
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHMP6 charged multivesicular body protein 6
COL11A2 collagen, type XI, alpha 2
CTAGE5 CTAGE family, member 5
CYB561 cytochrome b561
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLG4 discs, large homolog 4 (Drosophila)
ECSIT ECSIT signalling integrator
EGR1 early growth response 1
EML3 echinoderm microtubule associated protein like 3
FAM127B family with sequence similarity 127, member B
FLT1 fms-related tyrosine kinase 1
FST follistatin
FUS FUS RNA binding protein
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GPR107 G protein-coupled receptor 107
HDAC7 histone deacetylase 7
HIST1H1E histone cluster 1, H1e
HK2 hexokinase 2
HYI hydroxypyruvate isomerase (putative)
ICAM1 intercellular adhesion molecule 1
INF2 inverted formin, FH2 and WH2 domain containing
INHBA inhibin, beta A
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAT2 linker for activation of T cells family, member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAP4 microtubule-associated protein 4
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPS12 mitochondrial ribosomal protein S12
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NUMA1 nuclear mitotic apparatus protein 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAPOLA poly(A) polymerase alpha
PCCA propionyl CoA carboxylase, alpha polypeptide
PLSCR3 phospholipid scramblase 3
PMFBP1 polyamine modulated factor 1 binding protein 1
PORCN porcupine homolog (Drosophila)
PRDM2 PR domain containing 2, with ZNF domain
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RABGAP1L RAB GTPase activating protein 1-like
RANBP1 RAN binding protein 1
RC3H2 ring finger and CCCH-type domains 2
RGS10 regulator of G-protein signaling 10
RPL7 ribosomal protein L7
RRP1B ribosomal RNA processing 1B
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SIN3B SIN3 transcription regulator family member B
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNHG20 small nucleolar RNA host gene 20
STX1A syntaxin 1A (brain)
SUGP1 SURP and G patch domain containing 1
SYNJ2 synaptojanin 2
TAOK1 TAO kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
TCF3 transcription factor 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF1 TNF receptor-associated factor 1
TRAM2 translocation associated membrane protein 2
TUBB3 tubulin, beta 3 class III
TYMP thymidine phosphorylase
UNC45A unc-45 homolog A (C. elegans)
ZBTB40 zinc finger and BTB domain containing 40
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF137P zinc finger protein 137, pseudogene
ZNF500 zinc finger protein 500
ZNF552 zinc finger protein 552
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACOT13 acyl-CoA thioesterase 13
ADAM10 ADAM metallopeptidase domain 10
AIDA axin interactor, dorsalization associated
AKIP1 A kinase (PRKA) interacting protein 1
AKTIP AKT interacting protein
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APIP APAF1 interacting protein
ARHGAP12 Rho GTPase activating protein 12
ARID4A AT rich interactive domain 4A (RBP1-like)
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ASTE1 asteroid homolog 1 (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG2 BCL2-associated athanogene 2
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BBS10 Bardet-Biedl syndrome 10
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRIX1 BRX1, biogenesis of ribosomes
BTBD3 BTB (POZ) domain containing 3
C5 complement component 5
C5ORF30 chromosome 5 open reading frame 30
CASD1 CAS1 domain containing 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CDC37L1 cell division cycle 37-like 1
CGRRF1 cell growth regulator with ring finger domain 1
CLDND1 claudin domain containing 1
COMMD10 COMM domain containing 10
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTPS2 CTP synthase 2
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DENND4A DENN/MADD domain containing 4A
DNAAF2 dynein, axonemal, assembly factor 2
DPY19L4 dpy-19-like 4 (C. elegans)
ECHDC1 ethylmalonyl-CoA decarboxylase 1
ECI2 enoyl-CoA delta isomerase 2
EGR2 early growth response 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM222B family with sequence similarity 222, member B
FHL3 four and a half LIM domains 3
GSTCD glutathione S-transferase, C-terminal domain containing
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HMGB3P1 high mobility group box 3 pseudogene 1
HSPA4L heat shock 70kDa protein 4-like
IMPAD1 inositol monophosphatase domain containing 1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LMAN1 lectin, mannose-binding, 1
MANEA mannosidase, endo-alpha
MANSC1 MANSC domain containing 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFS1 NFS1 cysteine desulfurase
NMD3 NMD3 ribosome export adaptor
NT5M 5',3'-nucleotidase, mitochondrial
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PBX3 pre-B-cell leukemia homeobox 3
PCNXL4 pecanex-like 4 (Drosophila)
PITRM1 pitrilysin metallopeptidase 1
POGK pogo transposable element with KRAB domain
PRAF2 PRA1 domain family, member 2
PSAT1 phosphoserine aminotransferase 1
RAB4B RAB4B, member RAS oncogene family
RBM7 RNA binding motif protein 7
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNFT1 ring finger protein, transmembrane 1
RPE ribulose-5-phosphate-3-epimerase
SCYL2 SCY1-like 2 (S. cerevisiae)
SELT selenoprotein T
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SIRT2 sirtuin 2
SLC25A46 solute carrier family 25, member 46
SRD5A3 steroid 5 alpha-reductase 3
STBD1 starch binding domain 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TGIF1 TGFB-induced factor homeobox 1
THEM6 thioesterase superfamily member 6
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TRAPPC6A trafficking protein particle complex 6A
TRIM16 tripartite motif containing 16
UBFD1 ubiquitin family domain containing 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR5B WD repeat domain 5B
YIPF5 Yip1 domain family, member 5
ZBTB3 zinc finger and BTB domain containing 3
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF37BP zinc finger protein 37B, pseudogene
ZNF586 zinc finger protein 586
ZNF665 zinc finger protein 665