| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the cefalexin-2628 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ALCAM | activated leukocyte cell adhesion molecule |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATF6B | activating transcription factor 6 beta |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| ATXN2L | ataxin 2-like |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP1 | bone morphogenetic protein 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C22ORF31 | chromosome 22 open reading frame 31 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C3 | complement component 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CCKBR | cholecystokinin B receptor |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD58 | CD58 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| COL19A1 | collagen, type XIX, alpha 1 |
| CYTH1 | cytohesin 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| ERCC6 | excision repair cross-complementation group 6 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FRK | fyn-related Src family tyrosine kinase |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GLRA1 | glycine receptor, alpha 1 |
| GM2A | GM2 ganglioside activator |
| GYPB | glycophorin B (MNS blood group) |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HIST1H3F | histone cluster 1, H3f |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXC8 | homeobox C8 |
| ICAM1 | intercellular adhesion molecule 1 |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IRS2 | insulin receptor substrate 2 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB4 | integrin, beta 4 |
| JUN | jun proto-oncogene |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0319L | KIAA0319-like |
| KSR1 | kinase suppressor of ras 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYF5 | myogenic factor 5 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOF | myoferlin |
| NCOA2 | nuclear receptor coactivator 2 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NIN | ninein (GSK3B interacting protein) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRXN3 | neurexin 3 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OLFML2B | olfactomedin-like 2B |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCM1 | pericentriolar material 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDAP1 | PDGFA associated protein 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLP1 | proteolipid protein 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASL11B | RAS-like, family 11, member B |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RPS28 | ribosomal protein S28 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SEC24D | SEC24 family member D |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMAD3 | SMAD family member 3 |
| SP1 | Sp1 transcription factor |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST5 | suppression of tumorigenicity 5 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STX2 | syntaxin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYNGR1 | synaptogyrin 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| THBD | thrombomodulin |
| TLK1 | tousled-like kinase 1 |
| TMPRSS15 | transmembrane protease, serine 15 |
| UPK3B | uroplakin 3B |
| USP34 | ubiquitin specific peptidase 34 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WSCD1 | WSC domain containing 1 |
| ZNF154 | zinc finger protein 154 |
| ZNF3 | zinc finger protein 3 |
| ZNF639 | zinc finger protein 639 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BMP4 | bone morphogenetic protein 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5AR2 | complement component 5a receptor 2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLSPN | claspin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DUSP13 | dual specificity phosphatase 13 |
| EFNA3 | ephrin-A3 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC5 | exocyst complex component 5 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GAMT | guanidinoacetate N-methyltransferase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GRPR | gastrin-releasing peptide receptor |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED9 | mediator complex subunit 9 |
| METTL16 | methyltransferase like 16 |
| METTL2B | methyltransferase like 2B |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PARPBP | PARP1 binding protein |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF146 | ring finger protein 146 |
| S100A4 | S100 calcium binding protein A4 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRT6 | sirtuin 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNAI2 | snail family zinc finger 2 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAGLN | transgelin |
| TDRD1 | tudor domain containing 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAPPC2 | trafficking protein particle complex 2 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR13 | WD repeat domain 13 |
| WDR4 | WD repeat domain 4 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF254 | zinc finger protein 254 |
| ZNF446 | zinc finger protein 446 |
| ZNF573 | zinc finger protein 573 |
