| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cefalexin-5250 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOC4 | apolipoprotein C-IV |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATF7IP | activating transcription factor 7 interacting protein |
| BAIAP3 | BAI1-associated protein 3 |
| BMP1 | bone morphogenetic protein 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCNK | cyclin K |
| CD52 | CD52 molecule |
| CDH18 | cadherin 18, type 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEMP1 | cementum protein 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| DMXL2 | Dmx-like 2 |
| DOK4 | docking protein 4 |
| DST | dystonin |
| EFNB3 | ephrin-B3 |
| FAM182B | family with sequence similarity 182, member B |
| FAM188A | family with sequence similarity 188, member A |
| FAM63B | family with sequence similarity 63, member B |
| FBLN1 | fibulin 1 |
| FBXO40 | F-box protein 40 |
| FN1 | fibronectin 1 |
| FOXG1 | forkhead box G1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLRA2 | glycine receptor, alpha 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRM8 | glutamate receptor, metabotropic 8 |
| GRPR | gastrin-releasing peptide receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HBS1L | HBS1-like translational GTPase |
| HKDC1 | hexokinase domain containing 1 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXC4 | homeobox C4 |
| IFI35 | interferon-induced protein 35 |
| IFI44 | interferon-induced protein 44 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IRF9 | interferon regulatory factor 9 |
| ITGA7 | integrin, alpha 7 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC48 | leucine rich repeat containing 48 |
| MALL | mal, T-cell differentiation protein-like |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO15B | myosin XVB |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PDPN | podoplanin |
| PER2 | period circadian clock 2 |
| PHF7 | PHD finger protein 7 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLXNB3 | plexin B3 |
| PON3 | paraoxonase 3 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RASA3 | RAS p21 protein activator 3 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SSTR5 | somatostatin receptor 5 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SV2B | synaptic vesicle glycoprotein 2B |
| TAAR5 | trace amine associated receptor 5 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFEB | transcription factor EB |
| TMEM144 | transmembrane protein 144 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| UBXN1 | UBX domain protein 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VN1R1 | vomeronasal 1 receptor 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFF4 | AF4/FMR2 family, member 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC132 | coiled-coil domain containing 132 |
| CD82 | CD82 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CISH | cytokine inducible SH2-containing protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP2 | dual specificity phosphatase 2 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EVPL | envoplakin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GALT | galactose-1-phosphate uridylyltransferase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPX2 | glutathione peroxidase 2 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KLC2 | kinesin light chain 2 |
| KLF2 | Kruppel-like factor 2 |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRRC6 | leucine rich repeat containing 6 |
| LRRC61 | leucine rich repeat containing 61 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MTCP1 | mature T-cell proliferation 1 |
| MYO1F | myosin IF |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRAF2 | PRA1 domain family, member 2 |
| PRSS53 | protease, serine, 53 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RNF146 | ring finger protein 146 |
| RNF39 | ring finger protein 39 |
| RPL10L | ribosomal protein L10-like |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIX1 | SIX homeobox 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TMEM120B | transmembrane protein 120B |
| TRIM36 | tripartite motif containing 36 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| VASH1 | vasohibin 1 |
| VPS9D1 | VPS9 domain containing 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF282 | zinc finger protein 282 |
| ZNF747 | zinc finger protein 747 |
| ZNF787 | zinc finger protein 787 |
