| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the cefalexin-5615 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ANGPT4 | angiopoietin 4 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARSD | arylsulfatase D |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATXN3 | ataxin 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL17 | chemokine (C-C motif) ligand 17 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CNTNAP2 | contactin associated protein-like 2 |
| CUL7 | cullin 7 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DAO | D-amino-acid oxidase |
| DFNB31 | deafness, autosomal recessive 31 |
| EFCAB6 | EF-hand calcium binding domain 6 |
| EFNB3 | ephrin-B3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBLN1 | fibulin 1 |
| FBN1 | fibrillin 1 |
| FBXO40 | F-box protein 40 |
| FRMD4B | FERM domain containing 4B |
| FRZB | frizzled-related protein |
| FYB | FYN binding protein |
| FZD9 | frizzled class receptor 9 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GAS7 | growth arrest-specific 7 |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GLS | glutaminase |
| GPR161 | G protein-coupled receptor 161 |
| HAS1 | hyaluronan synthase 1 |
| HDAC6 | histone deacetylase 6 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIC2 | hypermethylated in cancer 2 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ICOS | inducible T-cell co-stimulator |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IRS2 | insulin receptor substrate 2 |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KHK | ketohexokinase (fructokinase) |
| KIAA1109 | KIAA1109 |
| KLHL22 | kelch-like family member 22 |
| KRT17 | keratin 17, type I |
| LAMB4 | laminin, beta 4 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LUZP4 | leucine zipper protein 4 |
| MAOA | monoamine oxidase A |
| MAPK8 | mitogen-activated protein kinase 8 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIP | major intrinsic protein of lens fiber |
| NEU2 | sialidase 2 (cytosolic sialidase) |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE12 | phosphodiesterase 12 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCL2 | phospholipase C-like 2 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PYY | peptide YY |
| RAB3B | RAB3B, member RAS oncogene family |
| REEP2 | receptor accessory protein 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RTCA | RNA 3'-terminal phosphate cyclase |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SFRP4 | secreted frizzled-related protein 4 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SPN | sialophorin |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPPL2B | signal peptide peptidase like 2B |
| SRGN | serglycin |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK11 | serine/threonine kinase 11 |
| TBR1 | T-box, brain, 1 |
| TBX2 | T-box 2 |
| TMEM63A | transmembrane protein 63A |
| TTPA | tocopherol (alpha) transfer protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADA | adenosine deaminase |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AFF4 | AF4/FMR2 family, member 4 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CCDC134 | coiled-coil domain containing 134 |
| CES3 | carboxylesterase 3 |
| CFD | complement factor D (adipsin) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLSTN2 | calsyntenin 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| DOCK4 | dedicator of cytokinesis 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM131A | family with sequence similarity 131, member A |
| FAM188A | family with sequence similarity 188, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FRMD1 | FERM domain containing 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GFI1 | growth factor independent 1 transcription repressor |
| GID4 | GID complex subunit 4 |
| GLI3 | GLI family zinc finger 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| H2AFJ | H2A histone family, member J |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| HPN | hepsin |
| INO80D | INO80 complex subunit D |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGMN | legumain |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC61 | leucine rich repeat containing 61 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MGC12488 | |
| MYO1E | myosin IE |
| NEK11 | NIMA-related kinase 11 |
| NME5 | NME/NM23 family member 5 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTX1 | neuronal pentraxin I |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRAGB | Ras-related GTP binding B |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGCE | sarcoglycan, epsilon |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMIM14 | small integral membrane protein 14 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYBU | syntabulin (syntaxin-interacting) |
| TAOK1 | TAO kinase 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBX19 | T-box 19 |
| TFF2 | trefoil factor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM45A | transmembrane protein 45A |
| TMEM53 | transmembrane protein 53 |
| TMEM62 | transmembrane protein 62 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TOLLIP | toll interacting protein |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TTBK2 | tau tubulin kinase 2 |
| UPK3B | uroplakin 3B |
| WDR4 | WD repeat domain 4 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF286A | zinc finger protein 286A |
| ZNF446 | zinc finger protein 446 |
| ZNF484 | zinc finger protein 484 |
| ZNF573 | zinc finger protein 573 |
| ZNF606 | zinc finger protein 606 |
| ZNF665 | zinc finger protein 665 |
