cefalonium-4245 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefalonium-4245 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
AHNAK AHNAK nucleoprotein
APOE apolipoprotein E
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATXN7L1 ataxin 7-like 1
BCL2 B-cell CLL/lymphoma 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTG2 BTG family, member 2
C21ORF2 chromosome 21 open reading frame 2
C22ORF24 chromosome 22 open reading frame 24
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CCDC121 coiled-coil domain containing 121
CCDC28B coiled-coil domain containing 28B
CCDC7 coiled-coil domain containing 7
CD6 CD6 molecule
CDC14A cell division cycle 14A
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CNTN1 contactin 1
COL4A6 collagen, type IV, alpha 6
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CSN3 casein kappa
CYBA cytochrome b-245, alpha polypeptide
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DMRT1 doublesex and mab-3 related transcription factor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPHA5 EPH receptor A5
EPS8L1 EPS8-like 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF18 fibroblast growth factor 18
FRMD4B FERM domain containing 4B
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAS2 growth arrest-specific 2
GAS7 growth arrest-specific 7
GK3P glycerol kinase 3 pseudogene
GLYAT glycine-N-acyltransferase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HAP1 huntingtin-associated protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HIPK3 homeodomain interacting protein kinase 3
HOXC11 homeobox C11
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI44 interferon-induced protein 44
IFT27 intraflagellar transport 27
IL1RN interleukin 1 receptor antagonist
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KRT32 keratin 32, type I
LMO1 LIM domain only 1 (rhombotin 1)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA8 melanoma antigen family A8
MIER2 mesoderm induction early response 1, family member 2
MMRN1 multimerin 1
MST1 macrophage stimulating 1
MTMR3 myotubularin related protein 3
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRP2 neuropilin 2
NTNG1 netrin G1
OXCT2 3-oxoacid CoA transferase 2
PDCD2 programmed cell death 2
PDE10A phosphodiesterase 10A
PGP phosphoglycolate phosphatase
PHOX2B paired-like homeobox 2b
PKNOX1 PBX/knotted 1 homeobox 1
PKP4 plakophilin 4
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PQLC2 PQ loop repeat containing 2
PRKG1 protein kinase, cGMP-dependent, type I
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRO protein tyrosine phosphatase, receptor type, O
RAB6B RAB6B, member RAS oncogene family
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMAD4 SMAD family member 4
SOCS3 suppressor of cytokine signaling 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBXA2R thromboxane A2 receptor
TMCC1 transmembrane and coiled-coil domain family 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM63A transmembrane protein 63A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TRD T cell receptor delta locus
TULP2 tubby like protein 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF214 zinc finger protein 214
ZNF268 zinc finger protein 268
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ADAM2 ADAM metallopeptidase domain 2
ALOX12 arachidonate 12-lipoxygenase
ALPK1 alpha-kinase 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
C14ORF105 chromosome 14 open reading frame 105
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CCL2 chemokine (C-C motif) ligand 2
CCNO cyclin O
CNOT3 CCR4-NOT transcription complex, subunit 3
COMP cartilage oligomeric matrix protein
CPNE7 copine VII
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
EDN1 endothelin 1
EFHD2 EF-hand domain family, member D2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM186A family with sequence similarity 186, member A
FAM86C1 family with sequence similarity 86, member C1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF20 fibroblast growth factor 20
FGL1 fibrinogen-like 1
FKBP5 FK506 binding protein 5
FURIN furin (paired basic amino acid cleaving enzyme)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPR75 G protein-coupled receptor 75
GRM4 glutamate receptor, metabotropic 4
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1T histone cluster 1, H1t
HIST1H2BN histone cluster 1, H2bn
HPR haptoglobin-related protein
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA17 interferon, alpha 17
IL36RN interleukin 36 receptor antagonist
KANSL3 KAT8 regulatory NSL complex subunit 3
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
LATS1 large tumor suppressor kinase 1
LENEP lens epithelial protein
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
LY6E lymphocyte antigen 6 complex, locus E
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MED31 mediator complex subunit 31
MFGE8 milk fat globule-EGF factor 8 protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTSS1L metastasis suppressor 1-like
MYL9 myosin, light chain 9, regulatory
MYO15A myosin XVA
MYO1F myosin IF
NDP Norrie disease (pseudoglioma)
NOTCH4 notch 4
NPFFR1 neuropeptide FF receptor 1
OSBP2 oxysterol binding protein 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIP prolactin-induced protein
PODNL1 podocan-like 1
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
PRKG2 protein kinase, cGMP-dependent, type II
PRM2 protamine 2
PRSS8 protease, serine, 8
QPCTL glutaminyl-peptide cyclotransferase-like
RAPSN receptor-associated protein of the synapse
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGCC regulator of cell cycle
SAYSD1 SAYSVFN motif domain containing 1
SCAMP4 secretory carrier membrane protein 4
SCARA3 scavenger receptor class A, member 3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIX3 SIX homeobox 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOX12 SRY (sex determining region Y)-box 12
SRD5A3 steroid 5 alpha-reductase 3
TBC1D17 TBC1 domain family, member 17
TBKBP1 TBK1 binding protein 1
TIGD6 tigger transposable element derived 6
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TSNAXIP1 translin-associated factor X interacting protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
WNT1 wingless-type MMTV integration site family, member 1
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF480 zinc finger protein 480
ZYX zyxin