cefamandole-3436 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cefamandole-3436 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAP1 ArfGAP with dual PH domains 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
APC adenomatous polyposis coli
ARHGAP1 Rho GTPase activating protein 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BPGM 2,3-bisphosphoglycerate mutase
CCNO cyclin O
CD200 CD200 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK20 cyclin-dependent kinase 20
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLTA clathrin, light chain A
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1 colony stimulating factor 1 (macrophage)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF8 DDB1 and CUL4 associated factor 8
E2F4 E2F transcription factor 4, p107/p130-binding
EML2 echinoderm microtubule associated protein like 2
EXTL3 exostosin-like glycosyltransferase 3
FGFR4 fibroblast growth factor receptor 4
FLOT2 flotillin 2
FRMD4B FERM domain containing 4B
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GREB1L growth regulation by estrogen in breast cancer-like
GSTCD glutathione S-transferase, C-terminal domain containing
GYG2 glycogenin 2
H2AFX H2A histone family, member X
HIST1H1D histone cluster 1, H1d
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOMER3 homer scaffolding protein 3
IDI2-AS1 IDI2 antisense RNA 1
INCENP inner centromere protein antigens 135/155kDa
ITM2C integral membrane protein 2C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KITLG KIT ligand
KLHL22 kelch-like family member 22
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMNB1 lamin B1
LTBP4 latent transforming growth factor beta binding protein 4
LUZP1 leucine zipper protein 1
LYPD1 LY6/PLAUR domain containing 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8 mitogen-activated protein kinase 8
MCM3AP minichromosome maintenance complex component 3 associated protein
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTA2 metastasis associated 1 family, member 2
MTMR1 myotubularin related protein 1
MUC1 mucin 1, cell surface associated
MYL10 myosin, light chain 10, regulatory
NF2 neurofibromin 2 (merlin)
NRF1 nuclear respiratory factor 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCDHA9 protocadherin alpha 9
PCM1 pericentriolar material 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFB platelet-derived growth factor beta polypeptide
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLEC plectin
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLLP plasmolipin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSD4 pleckstrin and Sec7 domain containing 4
PTPRE protein tyrosine phosphatase, receptor type, E
RCAN1 regulator of calcineurin 1
RIF1 replication timing regulatory factor 1
RND2 Rho family GTPase 2
RNF6 ring finger protein (C3H2C3 type) 6
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SRCAP Snf2-related CREBBP activator protein
TCP11L1 t-complex 11, testis-specific-like 1
TET3 tet methylcytosine dioxygenase 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TK2 thymidine kinase 2, mitochondrial
TMEM209 transmembrane protein 209
TNK1 tyrosine kinase, non-receptor, 1
TNPO2 transportin 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UCN urocortin
WDFY3 WD repeat and FYVE domain containing 3
WDR55 WD repeat domain 55

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFF4 AF4/FMR2 family, member 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
B9D2 B9 protein domain 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCORL1 BCL6 corepressor-like 1
CALCOCO1 calcium binding and coiled-coil domain 1
CCP110 centriolar coiled coil protein 110kDa
CDK3 cyclin-dependent kinase 3
CEP170B centrosomal protein 170B
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRLF1 cytokine receptor-like factor 1
CTSK cathepsin K
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EPPK1 epiplakin 1
FAM114A1 family with sequence similarity 114, member A1
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GPX2 glutathione peroxidase 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
IMPACT impact RWD domain protein
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KLC2 kinesin light chain 2
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NIPAL2 NIPA-like domain containing 2
NT5DC3 5'-nucleotidase domain containing 3
NUBPL nucleotide binding protein-like
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
P3H1 prolyl 3-hydroxylase 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G3 phospholipase A2, group III
PNRC1 proline-rich nuclear receptor coactivator 1
POMZP3 POM121 and ZP3 fusion
POTEKP POTE ankyrin domain family, member K, pseudogene
RASAL1 RAS protein activator like 1 (GAP1 like)
RCOR3 REST corepressor 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC41A3 solute carrier family 41, member 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOWAHC sosondowah ankyrin repeat domain family member C
TAGLN transgelin
THRAP3 thyroid hormone receptor associated protein 3
TM6SF1 transmembrane 6 superfamily member 1
TRIM5 tripartite motif containing 5
TSPAN5 tetraspanin 5
TSPYL2 TSPY-like 2
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF189 zinc finger protein 189
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF74 zinc finger protein 74
ZSCAN2 zinc finger and SCAN domain containing 2