cefamandole-3696 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefamandole-3696 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADD2 adducin 2 (beta)
AHNAK AHNAK nucleoprotein
AMELY amelogenin, Y-linked
ARR3 arrestin 3, retinal (X-arrestin)
ATAT1 alpha tubulin acetyltransferase 1
ATP10A ATPase, class V, type 10A
C19ORF26 chromosome 19 open reading frame 26
C1ORF61 chromosome 1 open reading frame 61
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML3 calmodulin-like 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CDC14B cell division cycle 14B
CDK13 cyclin-dependent kinase 13
CDX1 caudal type homeobox 1
CES1 carboxylesterase 1
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CREBZF CREB/ATF bZIP transcription factor
DAPK2 death-associated protein kinase 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DNAAF1 dynein, axonemal, assembly factor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDA ectodysplasin A
EGR1 early growth response 1
EMC3 ER membrane protein complex subunit 3
ESR1 estrogen receptor 1
FGB fibrinogen beta chain
FGF3 fibroblast growth factor 3
FGFR4 fibroblast growth factor receptor 4
FXYD2 FXYD domain containing ion transport regulator 2
GAP43 growth associated protein 43
GGT1 gamma-glutamyltransferase 1
GRM2 glutamate receptor, metabotropic 2
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAS1 hyaluronan synthase 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HN1L hematological and neurological expressed 1-like
HP haptoglobin
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL22RA1 interleukin 22 receptor, alpha 1
IZUMO4 IZUMO family member 4
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLHL18 kelch-like family member 18
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIMK1 LIM domain kinase 1
LMTK1 lemur tail kinase 1
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MRC2 mannose receptor, C type 2
MYO7B myosin VIIB
N4BP1 NEDD4 binding protein 1
NELL2 NEL-like 2 (chicken)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NME5 NME/NM23 family member 5
NOTCH4 notch 4
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY2R neuropeptide Y receptor Y2
OLFM1 olfactomedin 1
PBX1 pre-B-cell leukemia homeobox 1
PDCD2 programmed cell death 2
PDPN podoplanin
PMFBP1 polyamine modulated factor 1 binding protein 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTCH2 patched 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PYY peptide YY
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAVER2 ribonucleoprotein, PTB-binding 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RIMS3 regulating synaptic membrane exocytosis 3
RUNX1 runt-related transcription factor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERHL2 serine hydrolase-like 2
SHOX2 short stature homeobox 2
SLAMF7 SLAM family member 7
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNX13 sorting nexin 13
SOCS7 suppressor of cytokine signaling 7
SPHK2 sphingosine kinase 2
SSX3 synovial sarcoma, X breakpoint 3
SYT11 synaptotagmin XI
SYT2 synaptotagmin II
TBC1D30 TBC1 domain family, member 30
TBX1 T-box 1
TPM3 tropomyosin 3
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
TULP2 tubby like protein 2
VAX2 ventral anterior homeobox 2
ZNF391 zinc finger protein 391

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADTRP androgen-dependent TFPI-regulating protein
AIRE autoimmune regulator
ALPK3 alpha-kinase 3
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
AURKC aurora kinase C
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CBX4 chromobox homolog 4
CCDC121 coiled-coil domain containing 121
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CDK20 cyclin-dependent kinase 20
CLCN6 chloride channel, voltage-sensitive 6
CLEC2B C-type lectin domain family 2, member B
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTN1 contactin 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPB1 carboxypeptidase B1 (tissue)
CYBRD1 cytochrome b reductase 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FLJ22184
GJA8 gap junction protein, alpha 8, 50kDa
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
H2AFJ H2A histone family, member J
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
IFI35 interferon-induced protein 35
IFNA17 interferon, alpha 17
INF2 inverted formin, FH2 and WH2 domain containing
IQCC IQ motif containing C
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM8 lysine (K)-specific demethylase 8
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LRRC6 leucine rich repeat containing 6
MAP3K7CL MAP3K7 C-terminal like
MEIS3P1 Meis homeobox 3 pseudogene 1
MFGE8 milk fat globule-EGF factor 8 protein
MT1M metallothionein 1M
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCALD neurocalcin delta
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSMR oncostatin M receptor
PADI1 peptidyl arginine deiminase, type I
PAQR5 progestin and adipoQ receptor family member V
PDE12 phosphodiesterase 12
PGP phosphoglycolate phosphatase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTK6 protein tyrosine kinase 6
RABL6 RAB, member RAS oncogene family-like 6
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL3S RFPL3 antisense
RNF39 ring finger protein 39
SETD1A SET domain containing 1A
SLC16A6 solute carrier family 16, member 6
SLC46A3 solute carrier family 46, member 3
SPTBN2 spectrin, beta, non-erythrocytic 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAB2 stabilin 2
TAGLN3 transgelin 3
TBKBP1 TBK1 binding protein 1
TESPA1 thymocyte expressed, positive selection associated 1
THBS3 thrombospondin 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TSPAN8 tetraspanin 8
TUBA3C tubulin, alpha 3c
WDR33 WD repeat domain 33
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF671 zinc finger protein 671