cefapirin-2730 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the cefapirin-2730 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ALOXE3 arachidonate lipoxygenase 3
ARSB arylsulfatase B
ASPHD1 aspartate beta-hydroxylase domain containing 1
AURKA aurora kinase A
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BTN3A1 butyrophilin, subfamily 3, member A1
C10ORF95 chromosome 10 open reading frame 95
C3ORF36 chromosome 3 open reading frame 36
C8ORF17 chromosome 8 open reading frame 17
CASZ1 castor zinc finger 1
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDO1 cysteine dioxygenase type 1
COL8A2 collagen, type VIII, alpha 2
COLEC10 collectin sub-family member 10 (C-type lectin)
DCAF15 DDB1 and CUL4 associated factor 15
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DMP1 dentin matrix acidic phosphoprotein 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP4 dual specificity phosphatase 4
EDNRA endothelin receptor type A
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EXTL3 exostosin-like glycosyltransferase 3
FAM110B family with sequence similarity 110, member B
FAM46C family with sequence similarity 46, member C
FBP1 fructose-1,6-bisphosphatase 1
FBXL2 F-box and leucine-rich repeat protein 2
FGFBP1 fibroblast growth factor binding protein 1
FZD10 frizzled class receptor 10
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR137 G protein-coupled receptor 137
GPR176 G protein-coupled receptor 176
HLA-F major histocompatibility complex, class I, F
HOXA1 homeobox A1
HOXB5 homeobox B5
HSPA2 heat shock 70kDa protein 2
IL11 interleukin 11
IRF4 interferon regulatory factor 4
JAM2 junctional adhesion molecule 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KIF3A kinesin family member 3A
KRT17 keratin 17, type I
LHX6 LIM homeobox 6
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAOA monoamine oxidase A
MAPK11 mitogen-activated protein kinase 11
MARC1 mitochondrial amidoxime reducing component 1
MUC1 mucin 1, cell surface associated
MVB12B multivesicular body subunit 12B
MVD mevalonate (diphospho) decarboxylase
MX1 MX dynamin-like GTPase 1
NEU3 sialidase 3 (membrane sialidase)
NOTCH4 notch 4
NPPA natriuretic peptide A
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NUP188 nucleoporin 188kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCSK6 proprotein convertase subtilisin/kexin type 6
PLK4 polo-like kinase 4
PRUNE prune exopolyphosphatase
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB40AL RAB40A, member RAS oncogene family-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARG retinoic acid receptor, gamma
RBBP9 retinoblastoma binding protein 9
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS4 regulator of G-protein signaling 4
RGSL1 regulator of G-protein signaling like 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SOCS3 suppressor of cytokine signaling 3
SP140 SP140 nuclear body protein
SPHK1 sphingosine kinase 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STATH statherin
STK17A serine/threonine kinase 17a
SYNDIG1 synapse differentiation inducing 1
SYNPO synaptopodin
TAPT1 transmembrane anterior posterior transformation 1
TGFB1 transforming growth factor, beta 1
TMEM259 transmembrane protein 259
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRIP11 thyroid hormone receptor interactor 11
UTS2 urotensin 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)
XIST X inactive specific transcript (non-protein coding)
ZNF132 zinc finger protein 132
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADGRE3 adhesion G protein-coupled receptor E3
ANKH ANKH inorganic pyrophosphate transport regulator
ARMCX4 armadillo repeat containing, X-linked 4
ATG9A autophagy related 9A
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF53 chromosome 17 open reading frame 53
C22ORF46 chromosome 22 open reading frame 46
CCDC106 coiled-coil domain containing 106
CES3 carboxylesterase 3
CLEC2D C-type lectin domain family 2, member D
CLIP2 CAP-GLY domain containing linker protein 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSF1R colony stimulating factor 1 receptor
DOC2A double C2-like domains, alpha
DSPP dentin sialophosphoprotein
EGR2 early growth response 2
EHD3 EH-domain containing 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FAM184A family with sequence similarity 184, member A
FCHO1 FCH domain only 1
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FMOD fibromodulin
FOXD1 forkhead box D1
GK3P glycerol kinase 3 pseudogene
GPR75 G protein-coupled receptor 75
GRIP2 glutamate receptor interacting protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IP6K1 inositol hexakisphosphate kinase 1
IQSEC1 IQ motif and Sec7 domain 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUP junction plakoglobin
KDM8 lysine (K)-specific demethylase 8
KLF3 Kruppel-like factor 3 (basic)
LOC257152 uncharacterized LOC257152
LTC4S leukotriene C4 synthase
MEP1B meprin A, beta
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
NBEAL2 neurobeachin-like 2
NME8 NME/NM23 family member 8
NNAT neuronatin
NOD2 nucleotide-binding oligomerization domain containing 2
NT5E 5'-nucleotidase, ecto (CD73)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAQR6 progestin and adipoQ receptor family member VI
PARG poly (ADP-ribose) glycohydrolase
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PGP phosphoglycolate phosphatase
PITX2 paired-like homeodomain 2
PKD2L2 polycystic kidney disease 2-like 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCZ protein kinase C, zeta
PROS1 protein S (alpha)
PRSS53 protease, serine, 53
PYGB phosphorylase, glycogen; brain
RCAN3 RCAN family member 3
RNF121 ring finger protein 121
RWDD2A RWD domain containing 2A
SIK1 salt-inducible kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A8 solute carrier family 12, member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAS2R10 taste receptor, type 2, member 10
TBL1Y transducin (beta)-like 1, Y-linked
TBX19 T-box 19
TIGD6 tigger transposable element derived 6
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TNRC6B trinucleotide repeat containing 6B
TRIM36 tripartite motif containing 36
TSC22D4 TSC22 domain family, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBQLN4 ubiquilin 4
WNT10B wingless-type MMTV integration site family, member 10B
ZFHX4 zinc finger homeobox 4
ZMYM3 zinc finger, MYM-type 3
ZNF329 zinc finger protein 329
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778