cefapirin-3471 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefapirin-3471 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACVR1B activin A receptor, type IB
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANAPC13 anaphase promoting complex subunit 13
ARL4C ADP-ribosylation factor-like 4C
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF68 chromosome 2 open reading frame 68
C3ORF18 chromosome 3 open reading frame 18
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD3D CD3d molecule, delta (CD3-TCR complex)
CFLAR CASP8 and FADD-like apoptosis regulator
COL6A1 collagen, type VI, alpha 1
COPA coatomer protein complex, subunit alpha
CSF1 colony stimulating factor 1 (macrophage)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF15 DDB1 and CUL4 associated factor 15
DOCK9 dedicator of cytokinesis 9
DUSP4 dual specificity phosphatase 4
EDA ectodysplasin A
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM174B family with sequence similarity 174, member B
FAM46C family with sequence similarity 46, member C
FLJ22184
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAS6 growth arrest-specific 6
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GM2A GM2 ganglioside activator
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRM2 glutamate receptor, metabotropic 2
HCFC2 host cell factor C2
HDAC11 histone deacetylase 11
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
HPCAL4 hippocalcin like 4
ICA1 islet cell autoantigen 1, 69kDa
INADL InaD-like (Drosophila)
ISL1 ISL LIM homeobox 1
ITGB5 integrin, beta 5
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIAA0930 KIAA0930
LGALS2 lectin, galactoside-binding, soluble, 2
LHX6 LIM homeobox 6
LOC399491
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MSI1 musashi RNA-binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFX1 nuclear transcription factor, X-box binding 1
NRF1 nuclear respiratory factor 1
NT5DC3 5'-nucleotidase domain containing 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDH1 protocadherin 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PSEN2 presenilin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCTL glutaminyl-peptide cyclotransferase-like
RANBP1 RAN binding protein 1
RASAL2 RAS protein activator like 2
RER1 retention in endoplasmic reticulum sorting receptor 1
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
RIN3 Ras and Rab interactor 3
RNF19B ring finger protein 19B
RNF31 ring finger protein 31
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RYR1 ryanodine receptor 1 (skeletal)
SEC24D SEC24 family member D
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A17 solute carrier family 22, member 17
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX15 SRY (sex determining region Y)-box 15
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPON2 spondin 2, extracellular matrix protein
SRSF11 serine/arginine-rich splicing factor 11
STK38L serine/threonine kinase 38 like
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM6SF1 transmembrane 6 superfamily member 1
TRIO trio Rho guanine nucleotide exchange factor
UROD uroporphyrinogen decarboxylase
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WNT16 wingless-type MMTV integration site family, member 16
ZNF783 zinc finger family member 783
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD14A abhydrolase domain containing 14A
ADGRE5 adhesion G protein-coupled receptor E5
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
BCAS1 breast carcinoma amplified sequence 1
BCORL1 BCL6 corepressor-like 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C2ORF54 chromosome 2 open reading frame 54
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CAMTA2 calmodulin binding transcription activator 2
CAPG capping protein (actin filament), gelsolin-like
CASZ1 castor zinc finger 1
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CEP170B centrosomal protein 170B
CEP72 centrosomal protein 72kDa
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DEAF1 DEAF1 transcription factor
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FLT4 fms-related tyrosine kinase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GALT galactose-1-phosphate uridylyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPHN gephyrin
GPR143 G protein-coupled receptor 143
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BJ histone cluster 1, H2bj
HS1BP3 HCLS1 binding protein 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITPKC inositol-trisphosphate 3-kinase C
KDM5C lysine (K)-specific demethylase 5C
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC257152 uncharacterized LOC257152
LRP5 low density lipoprotein receptor-related protein 5
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MED9 mediator complex subunit 9
MICALL2 MICAL-like 2
MID1IP1 MID1 interacting protein 1
MRPL44 mitochondrial ribosomal protein L44
MTG1 mitochondrial ribosome-associated GTPase 1
MYL5 myosin, light chain 5, regulatory
NEK11 NIMA-related kinase 11
NT5E 5'-nucleotidase, ecto (CD73)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPH4 neurexophilin 4
OGFRL1 opioid growth factor receptor-like 1
OSMR oncostatin M receptor
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PGP phosphoglycolate phosphatase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPT2 palmitoyl-protein thioesterase 2
RASAL1 RAS protein activator like 1 (GAP1 like)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC38A10 solute carrier family 38, member 10
STBD1 starch binding domain 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCP2 synaptonemal complex protein 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
THOP1 thimet oligopeptidase 1
TMEM62 transmembrane protein 62
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN6 UBX domain protein 6
VARS valyl-tRNA synthetase
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
XAB2 XPA binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF473 zinc finger protein 473
ZNF652 zinc finger protein 652