cefapirin-6790 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cefapirin-6790 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAM23 ADAM metallopeptidase domain 23
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOE apolipoprotein E
APOM apolipoprotein M
ARHGAP44 Rho GTPase activating protein 44
ARMC4 armadillo repeat containing 4
BUD31 BUD31 homolog (S. cerevisiae)
C8A complement component 8, alpha polypeptide
CA9 carbonic anhydrase IX
CACFD1 calcium channel flower domain containing 1
CALD1 caldesmon 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCNK cyclin K
CD47 CD47 molecule
CLCN7 chloride channel, voltage-sensitive 7
CTIF CBP80/20-dependent translation initiation factor
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EPN1 epsin 1
ETV7 ets variant 7
FOXN2 forkhead box N2
FRMD1 FERM domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
GJA8 gap junction protein, alpha 8, 50kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPC3 glypican 3
GPR153 G protein-coupled receptor 153
HPS4 Hermansky-Pudlak syndrome 4
HYI hydroxypyruvate isomerase (putative)
IFI27 interferon, alpha-inducible protein 27
IFNA14 interferon, alpha 14
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
JAK2 Janus kinase 2
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL1 kelch-like family member 1
LAT2 linker for activation of T cells family, member 2
LEPR leptin receptor
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LMF2 lipase maturation factor 2
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGEC1 melanoma antigen family C1
MAPK7 mitogen-activated protein kinase 7
MIER2 mesoderm induction early response 1, family member 2
MMP19 matrix metallopeptidase 19
MMP3 matrix metallopeptidase 3
MTAP methylthioadenosine phosphorylase
MYH14 myosin, heavy chain 14, non-muscle
NCAN neurocan
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEB nebulin
NFX1 nuclear transcription factor, X-box binding 1
NOL12 nucleolar protein 12
NOP16 NOP16 nucleolar protein
NRSN2 neurensin 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDHA9 protocadherin alpha 9
PCDHB13 protocadherin beta 13
PDE4A phosphodiesterase 4A, cAMP-specific
PEAK1 pseudopodium-enriched atypical kinase 1
PIDD1 p53-induced death domain protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRMT2IP PRMT2 interacting protein
PTGES prostaglandin E synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGCC regulator of cell cycle
RND2 Rho family GTPase 2
RPL23 ribosomal protein L23
RUSC2 RUN and SH3 domain containing 2
SAFB2 scaffold attachment factor B2
SCG5 secretogranin V
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SRRT serrate, RNA effector molecule
ST7 suppression of tumorigenicity 7
TBX6 T-box 6
TMCC2 transmembrane and coiled-coil domain family 2
TOB2 transducer of ERBB2, 2
TPMT thiopurine S-methyltransferase
UBOX5 U-box domain containing 5
UPK2 uroplakin 2
VNN2 vanin 2
WDR62 WD repeat domain 62
ZBTB7A zinc finger and BTB domain containing 7A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ALPK1 alpha-kinase 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB1 arrestin, beta 1
BAX BCL2-associated X protein
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
CAMKMT calmodulin-lysine N-methyltransferase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CGA glycoprotein hormones, alpha polypeptide
CIDEC cell death-inducing DFFA-like effector c
CRABP1 cellular retinoic acid binding protein 1
CSF1R colony stimulating factor 1 receptor
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAZAP1 DAZ associated protein 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ELMO3 engulfment and cell motility 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM110B family with sequence similarity 110, member B
FAM189A2 family with sequence similarity 189, member A2
FBXL15 F-box and leucine-rich repeat protein 15
GAA glucosidase, alpha; acid
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GRB7 growth factor receptor-bound protein 7
GSTA4 glutathione S-transferase alpha 4
HDAC11 histone deacetylase 11
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
KIAA0125 KIAA0125
KIFC1 kinesin family member C1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MFAP2 microfibrillar-associated protein 2
MFSD11 major facilitator superfamily domain containing 11
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTERF1 mitochondrial transcription termination factor 1
MUM1 melanoma associated antigen (mutated) 1
NEK11 NIMA-related kinase 11
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPFFR1 neuropeptide FF receptor 1
OLFML2A olfactomedin-like 2A
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH12 protocadherin 12
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PGP phosphoglycolate phosphatase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPT2 palmitoyl-protein thioesterase 2
PTOV1 prostate tumor overexpressed 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCRN3 secernin 3
SDC3 syndecan 3
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
STK25 serine/threonine kinase 25
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TICAM1 toll-like receptor adaptor molecule 1
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
WDR91 WD repeat domain 91
ZBTB22 zinc finger and BTB domain containing 22
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF442 zinc finger protein 442
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZSCAN31 zinc finger and SCAN domain containing 31