| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the cefazolin-2564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACVR1B | activin A receptor, type IB |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AGRP | agouti related neuropeptide |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATF7 | activating transcription factor 7 |
| ATP9A | ATPase, class II, type 9A |
| BCL9 | B-cell CLL/lymphoma 9 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CD52 | CD52 molecule |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CD84 | CD84 molecule |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CLMN | calmin (calponin-like, transmembrane) |
| COL7A1 | collagen, type VII, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNMBP | dynamin binding protein |
| DTNB | dystrobrevin, beta |
| EMP1 | epithelial membrane protein 1 |
| EPN3 | epsin 3 |
| ERICH1 | glutamate-rich 1 |
| FLOT1 | flotillin 1 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GMPR | guanosine monophosphate reductase |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| HCFC1 | host cell factor C1 |
| HOXA10 | homeobox A10 |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| INSL4 | insulin-like 4 (placenta) |
| KIAA0754 | KIAA0754 |
| KLHL20 | kelch-like family member 20 |
| KLK7 | kallikrein-related peptidase 7 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRTAP1-3 | keratin associated protein 1-3 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIMK1 | LIM domain kinase 1 |
| LOC284244 | uncharacterized LOC284244 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAP7 | microtubule-associated protein 7 |
| MID1 | midline 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MSRB2 | methionine sulfoxide reductase B2 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDRG2 | NDRG family member 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME8 | NME/NM23 family member 8 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PARD3 | par-3 family cell polarity regulator |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLCH1 | phospholipase C, eta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM11 | PR domain containing 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| REC8 | REC8 meiotic recombination protein |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHOX2 | short stature homeobox 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC17A4 | solute carrier family 17, member 4 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TJP1 | tight junction protein 1 |
| TMOD1 | tropomodulin 1 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TOP3B | topoisomerase (DNA) III beta |
| TRAF1 | TNF receptor-associated factor 1 |
| TUBB1 | tubulin, beta 1 class VI |
| UBOX5 | U-box domain containing 5 |
| USP34 | ubiquitin specific peptidase 34 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFHX3 | zinc finger homeobox 3 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF821 | zinc finger protein 821 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABHD17B | abhydrolase domain containing 17B |
| AIRE | autoimmune regulator |
| AKTIP | AKT interacting protein |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ANKRD40 | ankyrin repeat domain 40 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| BMP15 | bone morphogenetic protein 15 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC9 | coiled-coil domain containing 9 |
| CD9 | CD9 molecule |
| CDA | cytidine deaminase |
| CDHR2 | cadherin-related family member 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP69 | cilia and flagella associated protein 69 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CPNE7 | copine VII |
| CTC1 | CTS telomere maintenance complex component 1 |
| DFNA5 | deafness, autosomal dominant 5 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DOC2A | double C2-like domains, alpha |
| DOK3 | docking protein 3 |
| DSPP | dentin sialophosphoprotein |
| FAM163A | family with sequence similarity 163, member A |
| FBXO31 | F-box protein 31 |
| FBXO40 | F-box protein 40 |
| FGF23 | fibroblast growth factor 23 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR68 | G protein-coupled receptor 68 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3I | histone cluster 1, H3i |
| HOXC8 | homeobox C8 |
| HSPA2 | heat shock 70kDa protein 2 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1456 | KIAA1456 |
| KPTN | kaptin (actin binding protein) |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC6 | leucine rich repeat containing 6 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MVD | mevalonate (diphospho) decarboxylase |
| MYOZ3 | myozenin 3 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NKX3-2 | NK3 homeobox 2 |
| NUBPL | nucleotide binding protein-like |
| PADI1 | peptidyl arginine deiminase, type I |
| PDLIM1 | PDZ and LIM domain 1 |
| PER3 | period circadian clock 3 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIPOX | pipecolic acid oxidase |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRDM12 | PR domain containing 12 |
| PRO2964 | uncharacterized protein PRO2964 |
| RAB13 | RAB13, member RAS oncogene family |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RETN | resistin |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEPW1 | selenoprotein W, 1 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STMN4 | stathmin-like 4 |
| SYTL2 | synaptotagmin-like 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAIP | TRAF interacting protein |
| TTC23 | tetratricopeptide repeat domain 23 |
| TXLNG | taxilin gamma |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR4 | WD repeat domain 4 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF280A | zinc finger protein 280A |
| ZNF675 | zinc finger protein 675 |