cefazolin-2564 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefazolin-2564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACVR1B activin A receptor, type IB
ADAM28 ADAM metallopeptidase domain 28
ADGRG1 adhesion G protein-coupled receptor G1
AGRP agouti related neuropeptide
ANKMY1 ankyrin repeat and MYND domain containing 1
ARHGAP26 Rho GTPase activating protein 26
ATF7 activating transcription factor 7
ATP9A ATPase, class II, type 9A
BCL9 B-cell CLL/lymphoma 9
C16ORF59 chromosome 16 open reading frame 59
CD52 CD52 molecule
CD58 CD58 molecule
CD6 CD6 molecule
CD84 CD84 molecule
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLMN calmin (calponin-like, transmembrane)
COL7A1 collagen, type VII, alpha 1
COPE coatomer protein complex, subunit epsilon
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DNMBP dynamin binding protein
DTNB dystrobrevin, beta
EMP1 epithelial membrane protein 1
EPN3 epsin 3
ERICH1 glutamate-rich 1
FLOT1 flotillin 1
FLRT1 fibronectin leucine rich transmembrane protein 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GMPR guanosine monophosphate reductase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HCFC1 host cell factor C1
HOXA10 homeobox A10
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IGHA1 immunoglobulin heavy constant alpha 1
INSL4 insulin-like 4 (placenta)
KIAA0754 KIAA0754
KLHL20 kelch-like family member 20
KLK7 kallikrein-related peptidase 7
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRTAP1-3 keratin associated protein 1-3
LAMB2 laminin, beta 2 (laminin S)
LEF1 lymphoid enhancer-binding factor 1
LIMK1 LIM domain kinase 1
LOC284244 uncharacterized LOC284244
MAML3 mastermind-like 3 (Drosophila)
MAP7 microtubule-associated protein 7
MID1 midline 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSRB2 methionine sulfoxide reductase B2
MTA2 metastasis associated 1 family, member 2
NDRG2 NDRG family member 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME8 NME/NM23 family member 8
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARD3 par-3 family cell polarity regulator
PARP3 poly (ADP-ribose) polymerase family, member 3
PLCH1 phospholipase C, eta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB1 proline-rich protein BstNI subfamily 1
PRDM11 PR domain containing 11
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RAP1GAP2 RAP1 GTPase activating protein 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REC8 REC8 meiotic recombination protein
RIMS2 regulating synaptic membrane exocytosis 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHOX2 short stature homeobox 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC17A4 solute carrier family 17, member 4
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPG20 spastic paraplegia 20 (Troyer syndrome)
STARD13 StAR-related lipid transfer (START) domain containing 13
THSD7A thrombospondin, type I, domain containing 7A
TJAP1 tight junction associated protein 1 (peripheral)
TJP1 tight junction protein 1
TMOD1 tropomodulin 1
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TOP3B topoisomerase (DNA) III beta
TRAF1 TNF receptor-associated factor 1
TUBB1 tubulin, beta 1 class VI
UBOX5 U-box domain containing 5
USP34 ubiquitin specific peptidase 34
ZBTB20 zinc finger and BTB domain containing 20
ZFHX3 zinc finger homeobox 3
ZMYND8 zinc finger, MYND-type containing 8
ZNF821 zinc finger protein 821
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABHD17B abhydrolase domain containing 17B
AIRE autoimmune regulator
AKTIP AKT interacting protein
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD40 ankyrin repeat domain 40
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BMP15 bone morphogenetic protein 15
C17ORF80 chromosome 17 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CD9 CD9 molecule
CDA cytidine deaminase
CDHR2 cadherin-related family member 2
CDK20 cyclin-dependent kinase 20
CFAP69 cilia and flagella associated protein 69
CLCN2 chloride channel, voltage-sensitive 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPNE7 copine VII
CTC1 CTS telomere maintenance complex component 1
DFNA5 deafness, autosomal dominant 5
DKFZP434L187 uncharacterized LOC26082
DOC2A double C2-like domains, alpha
DOK3 docking protein 3
DSPP dentin sialophosphoprotein
FAM163A family with sequence similarity 163, member A
FBXO31 F-box protein 31
FBXO40 F-box protein 40
FGF23 fibroblast growth factor 23
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR68 G protein-coupled receptor 68
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AJ histone cluster 1, H2aj
HIST1H3I histone cluster 1, H3i
HOXC8 homeobox C8
HSPA2 heat shock 70kDa protein 2
IGKV3-20 immunoglobulin kappa variable 3-20
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD15 potassium channel tetramerization domain containing 15
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1456 KIAA1456
KPTN kaptin (actin binding protein)
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00260 long intergenic non-protein coding RNA 260
LOC100287590 uncharacterized LOC100287590
LRRC6 leucine rich repeat containing 6
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBNL3 muscleblind-like splicing regulator 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MVD mevalonate (diphospho) decarboxylase
MYOZ3 myozenin 3
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NKX3-2 NK3 homeobox 2
NUBPL nucleotide binding protein-like
PADI1 peptidyl arginine deiminase, type I
PDLIM1 PDZ and LIM domain 1
PER3 period circadian clock 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIPOX pipecolic acid oxidase
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
PRDM12 PR domain containing 12
PRO2964 uncharacterized protein PRO2964
RAB13 RAB13, member RAS oncogene family
REPS2 RALBP1 associated Eps domain containing 2
RETN resistin
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SEPW1 selenoprotein W, 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STMN4 stathmin-like 4
SYTL2 synaptotagmin-like 2
TAS2R10 taste receptor, type 2, member 10
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TNRC6B trinucleotide repeat containing 6B
TRAIP TRAF interacting protein
TTC23 tetratricopeptide repeat domain 23
TXLNG taxilin gamma
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR4 WD repeat domain 4
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF280A zinc finger protein 280A
ZNF675 zinc finger protein 675