cefazolin-3426 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefazolin-3426 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APC adenomatous polyposis coli
APOM apolipoprotein M
AR androgen receptor
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARTN artemin
ATF7IP activating transcription factor 7 interacting protein
ATP9A ATPase, class II, type 9A
BAIAP3 BAI1-associated protein 3
BIRC7 baculoviral IAP repeat containing 7
BMP5 bone morphogenetic protein 5
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CDK12 cyclin-dependent kinase 12
CDRT1 CMT1A duplicated region transcript 1
CHML choroideremia-like (Rab escort protein 2)
COMT catechol-O-methyltransferase
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBP D site of albumin promoter (albumin D-box) binding protein
DCAF15 DDB1 and CUL4 associated factor 15
DLX2 distal-less homeobox 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EML2 echinoderm microtubule associated protein like 2
ENO3 enolase 3 (beta, muscle)
EPS8L1 EPS8-like 1
ERCC2 excision repair cross-complementation group 2
FXR2 fragile X mental retardation, autosomal homolog 2
GLP1R glucagon-like peptide 1 receptor
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H4C histone cluster 1, H4c
ICAM1 intercellular adhesion molecule 1
IDI2-AS1 IDI2 antisense RNA 1
IL6ST interleukin 6 signal transducer
IQCE IQ motif containing E
IQCG IQ motif containing G
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0754 KIAA0754
LAMA2 laminin, alpha 2
LOC647070 uncharacterized LOC647070
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGOH2P mago-nashi homolog 2, pseudogene
MATK megakaryocyte-associated tyrosine kinase
MCM9 minichromosome maintenance complex component 9
MYL10 myosin, light chain 10, regulatory
NF2 neurofibromin 2 (merlin)
NMT2 N-myristoyltransferase 2
NOL10 nucleolar protein 10
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NXPH4 neurexophilin 4
OAZ3 ornithine decarboxylase antizyme 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHB13 protocadherin beta 13
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RASA3 RAS p21 protein activator 3
RBM5 RNA binding motif protein 5
S100A11 S100 calcium binding protein A11
S100A8 S100 calcium binding protein A8
SH3GL3 SH3-domain GRB2-like 3
SIVA1 SIVA1, apoptosis-inducing factor
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SSPN sarcospan
STON1 stonin 1
SULT4A1 sulfotransferase family 4A, member 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D22A TBC1 domain family, member 22A
TDRKH tudor and KH domain containing
TFE3 transcription factor binding to IGHM enhancer 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMOD1 tropomodulin 1
TMPRSS15 transmembrane protease, serine 15
TOP3B topoisomerase (DNA) III beta
TRA2A transformer 2 alpha homolog (Drosophila)
TSHB thyroid stimulating hormone, beta
UBA7 ubiquitin-like modifier activating enzyme 7
ULK2 unc-51 like autophagy activating kinase 2
UNC119 unc-119 homolog (C. elegans)
UPP1 uridine phosphorylase 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
YY2 YY2 transcription factor
ZBTB44 zinc finger and BTB domain containing 44
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF277 zinc finger protein 277
ZNF506 zinc finger protein 506
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD3A ATPase family, AAA domain containing 3A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL2L2 BCL2-like 2
BCL9 B-cell CLL/lymphoma 9
BCOR BCL6 corepressor
CCDC25 coiled-coil domain containing 25
CCP110 centriolar coiled coil protein 110kDa
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEP72 centrosomal protein 72kDa
CFAP44 cilia and flagella associated protein 44
CHST10 carbohydrate sulfotransferase 10
CLCN2 chloride channel, voltage-sensitive 2
CLDN15 claudin 15
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPS7B COP9 signalosome subunit 7B
DENND4A DENN/MADD domain containing 4A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGKZ diacylglycerol kinase, zeta
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNM1 dynamin 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXL4 F-box and leucine-rich repeat protein 4
FBXW12 F-box and WD repeat domain containing 12
FHOD1 formin homology 2 domain containing 1
FOSL1 FOS-like antigen 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IL4R interleukin 4 receptor
IRF7 interferon regulatory factor 7
KCTD7 potassium channel tetramerization domain containing 7
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNB2 lamin B2
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LZTR1 leucine-zipper-like transcription regulator 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MICALL2 MICAL-like 2
MITF microphthalmia-associated transcription factor
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1D myosin ID
MYO1F myosin IF
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NT5DC3 5'-nucleotidase domain containing 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ODF2 outer dense fiber of sperm tails 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PODXL2 podocalyxin-like 2
PRR14L proline rich 14-like
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAB8B RAB8B, member RAS oncogene family
RBL1 retinoblastoma-like 1
REPS2 RALBP1 associated Eps domain containing 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIRAL2 SIR2 antiphage like 2
SIRT6 sirtuin 6
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG3 small nucleolar RNA host gene 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TPST1 tyrosylprotein sulfotransferase 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF189 zinc finger protein 189
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF574 zinc finger protein 574
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF767P zinc finger family member 767, pseudogene