cefazolin-3686 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefazolin-3686 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C1ORF68 chromosome 1 open reading frame 68
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
CCDC170 coiled-coil domain containing 170
CCDC186 coiled-coil domain containing 186
CCDC57 coiled-coil domain containing 57
CD58 CD58 molecule
CD8B CD8b molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEMIP cell migration inducing protein, hyaluronan binding
CFH complement factor H
CHI3L2 chitinase 3-like 2
CIB2 calcium and integrin binding family member 2
CIDEB cell death-inducing DFFA-like effector b
CLPS colipase, pancreatic
CNGB3 cyclic nucleotide gated channel beta 3
CTNS cystinosin, lysosomal cystine transporter
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DOCK9 dedicator of cytokinesis 9
DUX1 double homeobox 1
EGFR epidermal growth factor receptor
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPHA5 EPH receptor A5
FGFR4 fibroblast growth factor receptor 4
FN1 fibronectin 1
FSCN3 fascin actin-bundling protein 3, testicular
GFER growth factor, augmenter of liver regeneration
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXA3 homeobox A3
ICA1 islet cell autoantigen 1, 69kDa
IFT140 intraflagellar transport 140
IGFBP7 insulin-like growth factor binding protein 7
IL1RN interleukin 1 receptor antagonist
IL32 interleukin 32
KIF25 kinesin family member 25
KLHL18 kelch-like family member 18
KRT2 keratin 2, type II
KRT85 keratin 85, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LDAH lipid droplet associated hydrolase
LIPE lipase, hormone-sensitive
LMTK1 lemur tail kinase 1
MAST2 microtubule associated serine/threonine kinase 2
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYO9B myosin IXB
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHLH1 nescient helix loop helix 1
NME5 NME/NM23 family member 5
NTF3 neurotrophin 3
OSBP2 oxysterol binding protein 2
OVOL1 ovo-like zinc finger 1
PAPOLG poly(A) polymerase gamma
PCDHB13 protocadherin beta 13
PER2 period circadian clock 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PNMA3 paraneoplastic Ma antigen 3
POU3F4 POU class 3 homeobox 4
PVR poliovirus receptor
PYY peptide YY
RAB5C RAB5C, member RAS oncogene family
RANBP3 RAN binding protein 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH2D3A SH2 domain containing 3A
SHOX2 short stature homeobox 2
SIX3 SIX homeobox 3
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPRR2B small proline-rich protein 2B
SPTBN1 spectrin, beta, non-erythrocytic 1
TAS2R1 taste receptor, type 2, member 1
TBL1Y transducin (beta)-like 1, Y-linked
TBX1 T-box 1
TFEB transcription factor EB
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF4 TNF receptor-associated factor 4
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TSC2 tuberous sclerosis 2
TSPY1 testis specific protein, Y-linked 1
TTLL5 tubulin tyrosine ligase-like family member 5
TULP1 tubby like protein 1
UBE2B ubiquitin-conjugating enzyme E2B
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
WAS Wiskott-Aldrich syndrome
WIZ widely interspaced zinc finger motifs
WTAP Wilms tumor 1 associated protein
ZBTB7A zinc finger and BTB domain containing 7A
ZIC3 Zic family member 3
ZSCAN32 zinc finger and SCAN domain containing 32
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADGRE2 adhesion G protein-coupled receptor E2
AGMAT agmatine ureohydrolase (agmatinase)
ALPK3 alpha-kinase 3
ALPP alkaline phosphatase, placental
ANKH ANKH inorganic pyrophosphate transport regulator
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APH1B APH1B gamma secretase subunit
ARPIN actin-related protein 2/3 complex inhibitor
BDKRB1 bradykinin receptor B1
CA9 carbonic anhydrase IX
CCNO cyclin O
CD70 CD70 molecule
CDHR2 cadherin-related family member 2
CLEC4E C-type lectin domain family 4, member E
CNTLN centlein, centrosomal protein
CORO1A coronin, actin binding protein, 1A
CPZ carboxypeptidase Z
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
ETV6 ets variant 6
FAM110B family with sequence similarity 110, member B
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
FRS3 fibroblast growth factor receptor substrate 3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR3 G protein-coupled receptor 3
GRAMD1C GRAM domain containing 1C
HDAC11 histone deacetylase 11
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST2H2AA3 histone cluster 2, H2aa3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA2 homeobox A2
HOXB9 homeobox B9
HOXC11 homeobox C11
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IGFLR1 IGF-like family receptor 1
IQCC IQ motif containing C
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA1107 KIAA1107
KLHL36 kelch-like family member 36
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LMO7 LIM domain 7
MED15 mediator complex subunit 15
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MFGE8 milk fat globule-EGF factor 8 protein
MNX1 motor neuron and pancreas homeobox 1
NEK11 NIMA-related kinase 11
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PICK1 protein interacting with PRKCA 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODNL1 podocan-like 1
POMT1 protein-O-mannosyltransferase 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PWAR5 Prader Willi/Angelman region RNA 5
RASL11B RAS-like, family 11, member B
RGCC regulator of cell cycle
RHBDD3 rhomboid domain containing 3
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPTBN2 spectrin, beta, non-erythrocytic 2
SYNGR3 synaptogyrin 3
TFCP2L1 transcription factor CP2-like 1
TMSB15A thymosin beta 15a
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VASH1 vasohibin 1
VGLL3 vestigial-like family member 3
ZBTB22 zinc finger and BTB domain containing 22
ZFP30 ZFP30 zinc finger protein
ZNF350 zinc finger protein 350
ZNF415 zinc finger protein 415
ZNF639 zinc finger protein 639
ZNF667 zinc finger protein 667