cefazolin-4708 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cefazolin-4708 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM22 ADAM metallopeptidase domain 22
ADGRG2 adhesion G protein-coupled receptor G2
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADRBK1 adrenergic, beta, receptor kinase 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMPD3 adenosine monophosphate deaminase 3
ANGEL2 angel homolog 2 (Drosophila)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARMCX2 armadillo repeat containing, X-linked 2
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN3 ataxin 3
BAAT bile acid CoA:amino acid N-acyltransferase
BHLHE40 basic helix-loop-helix family, member e40
BTD biotinidase
CCDC121 coiled-coil domain containing 121
CDK18 cyclin-dependent kinase 18
CFLAR CASP8 and FADD-like apoptosis regulator
COPA coatomer protein complex, subunit alpha
CRYGD crystallin, gamma D
CXCR4 chemokine (C-X-C motif) receptor 4
EDN1 endothelin 1
EFNA3 ephrin-A3
EPS8L1 EPS8-like 1
EXTL3 exostosin-like glycosyltransferase 3
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FRMD4A FERM domain containing 4A
FRMD4B FERM domain containing 4B
GBP2 guanylate binding protein 2, interferon-inducible
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GID4 GID complex subunit 4
GJA8 gap junction protein, alpha 8, 50kDa
GK glycerol kinase
GPATCH4 G patch domain containing 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H2BC histone cluster 1, H2bc
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
IL22 interleukin 22
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIFC3 kinesin family member C3
LAMP1 lysosomal-associated membrane protein 1
MED31 mediator complex subunit 31
MST1 macrophage stimulating 1
MTCP1 mature T-cell proliferation 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
N4BP2L1 NEDD4 binding protein 2-like 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NLRX1 NLR family member X1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ONECUT2 one cut homeobox 2
PAOX polyamine oxidase (exo-N4-amino)
PARG poly (ADP-ribose) glycohydrolase
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PEX16 peroxisomal biogenesis factor 16
PLD2 phospholipase D2
PLK4 polo-like kinase 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRLR prolactin receptor
PRSS16 protease, serine, 16 (thymus)
PRY PTPN13-like, Y-linked
PSG6 pregnancy specific beta-1-glycoprotein 6
PTHLH parathyroid hormone-like hormone
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
QKI QKI, KH domain containing, RNA binding
RAD54B RAD54 homolog B (S. cerevisiae)
RBBP9 retinoblastoma binding protein 9
RFPL2 ret finger protein-like 2
RFXAP regulatory factor X-associated protein
RPL10L ribosomal protein L10-like
RPS3A ribosomal protein S3A
SAP30 Sin3A-associated protein, 30kDa
SAYSD1 SAYSVFN motif domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLAMF7 SLAM family member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SOAT1 sterol O-acyltransferase 1
SPINK4 serine peptidase inhibitor, Kazal type 4
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TJAP1 tight junction associated protein 1 (peripheral)
TM4SF4 transmembrane 4 L six family member 4
TMEM144 transmembrane protein 144
TRAPPC9 trafficking protein particle complex 9
TRPM2 transient receptor potential cation channel, subfamily M, member 2
YIPF4 Yip1 domain family, member 4
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF750 zinc finger protein 750
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
C14ORF132 chromosome 14 open reading frame 132
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
C2ORF54 chromosome 2 open reading frame 54
CCDC69 coiled-coil domain containing 69
CCDC85C coiled-coil domain containing 85C
CDADC1 cytidine and dCMP deaminase domain containing 1
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CRYGC crystallin, gamma C
DCAF13 DDB1 and CUL4 associated factor 13
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNALI1 dynein, axonemal, light intermediate chain 1
DPY19L1P1 DPY19L1 pseudogene 1
ELSPBP1 epididymal sperm binding protein 1
EXD3 exonuclease 3'-5' domain containing 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM46C family with sequence similarity 46, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF23 fibroblast growth factor 23
FLJ22184
FLT4 fms-related tyrosine kinase 4
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSPB6 heat shock protein, alpha-crystallin-related, B6
HYI hydroxypyruvate isomerase (putative)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RA interleukin 17 receptor A
KDM7A lysine (K)-specific demethylase 7A
KLHL25 kelch-like family member 25
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT15 keratin 15, type I
KRT31 keratin 31, type I
LIG4 ligase IV, DNA, ATP-dependent
LMO2 LIM domain only 2 (rhombotin-like 1)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MYLK myosin light chain kinase
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD4 neuronal differentiation 4
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NPPB natriuretic peptide B
NPR3 natriuretic peptide receptor 3
NT5E 5'-nucleotidase, ecto (CD73)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE12 phosphodiesterase 12
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMEL premelanosome protein
POLM polymerase (DNA directed), mu
PRB3 proline-rich protein BstNI subfamily 3
PRR14L proline rich 14-like
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
SAA3P serum amyloid A3 pseudogene
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A8 solute carrier family 12, member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPAG7 sperm associated antigen 7
SPRR2B small proline-rich protein 2B
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STIM1 stromal interaction molecule 1
STRN striatin, calmodulin binding protein
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
ZBTB22 zinc finger and BTB domain containing 22
ZC3H3 zinc finger CCCH-type containing 3
ZNF134 zinc finger protein 134
ZNF250 zinc finger protein 250
ZNF480 zinc finger protein 480
ZNF74 zinc finger protein 74