| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cefepime-3581 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| B9D2 | B9 protein domain 2 |
| BGN | biglycan |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C2 | complement component 2 |
| CACTIN | cactin, spliceosome C complex subunit |
| CALML3 | calmodulin-like 3 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CD4 | CD4 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDHR2 | cadherin-related family member 2 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DOK4 | docking protein 4 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EPHB2 | EPH receptor B2 |
| ETNK2 | ethanolamine kinase 2 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FBXO31 | F-box protein 31 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR153 | G protein-coupled receptor 153 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HMGA1 | high mobility group AT-hook 1 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOMER3 | homer scaffolding protein 3 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT54 | intraflagellar transport 54 |
| IGL | immunoglobulin lambda locus |
| JADE2 | jade family PHD finger 2 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LMF2 | lipase maturation factor 2 |
| LOC399491 | |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MMP25 | matrix metallopeptidase 25 |
| MPZ | myelin protein zero |
| MVD | mevalonate (diphospho) decarboxylase |
| MYT1 | myelin transcription factor 1 |
| NDRG2 | NDRG family member 2 |
| NKX3-2 | NK3 homeobox 2 |
| NOX1 | NADPH oxidase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRL | neural retina leucine zipper |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUP188 | nucleoporin 188kDa |
| OCLM | oculomedin |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDZD2 | PDZ domain containing 2 |
| PDZRN4 | PDZ domain containing ring finger 4 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PITX1 | paired-like homeodomain 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| RCAN3 | RCAN family member 3 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF19B | ring finger protein 19B |
| S100A8 | S100 calcium binding protein A8 |
| SASH3 | SAM and SH3 domain containing 3 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SP100 | SP100 nuclear antigen |
| STK11 | serine/threonine kinase 11 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNJ2 | synaptojanin 2 |
| TAZ | tafazzin |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLK1 | tousled-like kinase 1 |
| TMEM8B | transmembrane protein 8B |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TSPAN32 | tetraspanin 32 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBA4B | tubulin, alpha 4b |
| UBQLN4 | ubiquilin 4 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WDR55 | WD repeat domain 55 |
| WTAP | Wilms tumor 1 associated protein |
| ZNF639 | zinc finger protein 639 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARRB1 | arrestin, beta 1 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLGN | calmegin |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTAGE9 | CTAGE family, member 9 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EMID1 | EMI domain containing 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXO5 | exonuclease 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FGF23 | fibroblast growth factor 23 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAS2 | growth arrest-specific 2 |
| GPC3 | glypican 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HOXC8 | homeobox C8 |
| HOXD11 | homeobox D11 |
| IFT140 | intraflagellar transport 140 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IPO8 | importin 8 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT24 | keratin 24, type I |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC20 | leucine rich repeat containing 20 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEA6 | melanoma antigen family A6 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| MYO1E | myosin IE |
| NLGN1 | neuroligin 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NRTN | neurturin |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHB8 | protocadherin beta 8 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLL | polymerase (DNA directed), lambda |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAB3D | RAB3D, member RAS oncogene family |
| RFPL1S | RFPL1 antisense RNA 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCARA3 | scavenger receptor class A, member 3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SHROOM2 | shroom family member 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| VASH1 | vasohibin 1 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF10 | zinc finger protein 10 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF423 | zinc finger protein 423 |
