cefepime-5761 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the cefepime-5761 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADD2 adducin 2 (beta)
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
BMP10 bone morphogenetic protein 10
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C2ORF72 chromosome 2 open reading frame 72
CA9 carbonic anhydrase IX
CALB2 calbindin 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD80 CD80 molecule
CDH8 cadherin 8, type 2
CFAP69 cilia and flagella associated protein 69
CLCN7 chloride channel, voltage-sensitive 7
CLEC4M C-type lectin domain family 4, member M
COL14A1 collagen, type XIV, alpha 1
COL7A1 collagen, type VII, alpha 1
CORO1A coronin, actin binding protein, 1A
CROCC ciliary rootlet coiled-coil, rootletin
CYBA cytochrome b-245, alpha polypeptide
DKFZP434C153 DKFZP434C153 protein
DMXL2 Dmx-like 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
F9 coagulation factor IX
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLJ11292
FLRT2 fibronectin leucine rich transmembrane protein 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGT1 gamma-glutamyltransferase 1
GOSR2 golgi SNAP receptor complex member 2
GP1BB glycoprotein Ib (platelet), beta polypeptide
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
HEMK1 HemK methyltransferase family member 1
HIST1H3A histone cluster 1, H3a
HIST1H4E histone cluster 1, H4e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPCAL4 hippocalcin like 4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL1R1 interleukin 1 receptor, type I
IRX4 iroquois homeobox 4
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KDM8 lysine (K)-specific demethylase 8
KRT38 keratin 38, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMO2 LIM domain only 2 (rhombotin-like 1)
MED16 mediator complex subunit 16
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPS18C mitochondrial ribosomal protein S18C
MTMR1 myotubularin related protein 1
MTSS1L metastasis suppressor 1-like
NCR2 natural cytotoxicity triggering receptor 2
NEK11 NIMA-related kinase 11
NPPA natriuretic peptide A
NPTX1 neuronal pentraxin I
NRN1 neuritin 1
ONECUT2 one cut homeobox 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE12 phosphodiesterase 12
PDE4D phosphodiesterase 4D, cAMP-specific
PICALM phosphatidylinositol binding clathrin assembly protein
PLA2G10 phospholipase A2, group X
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PRSS22 protease, serine, 22
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RBMS2 RNA binding motif, single stranded interacting protein 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SERHL2 serine hydrolase-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A4 solute carrier family 17, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SOX30 SRY (sex determining region Y)-box 30
SP1 Sp1 transcription factor
STRA6 stimulated by retinoic acid 6
TAS2R16 taste receptor, type 2, member 16
TBC1D22B TBC1 domain family, member 22B
TGFA transforming growth factor, alpha
TLR1 toll-like receptor 1
TMEM246 transmembrane protein 246
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSKS testis-specific serine kinase substrate
USF2 upstream transcription factor 2, c-fos interacting
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA10 annexin A10
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP15 bone morphogenetic protein 15
C1RL complement component 1, r subcomponent-like
CA8 carbonic anhydrase VIII
CCNJL cyclin J-like
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CISH cytokine inducible SH2-containing protein
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRLF1 cytokine receptor-like factor 1
CRY2 cryptochrome circadian clock 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DLL3 delta-like 3 (Drosophila)
EN2 engrailed homeobox 2
EPHA5 EPH receptor A5
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL2 F-box and leucine-rich repeat protein 2
FGL1 fibrinogen-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAL3ST4 galactose-3-O-sulfotransferase 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HINFP histone H4 transcription factor
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
IFI6 interferon, alpha-inducible protein 6
IL20RA interleukin 20 receptor, alpha
IL6 interleukin 6
IMPACT impact RWD domain protein
KCTD17 potassium channel tetramerization domain containing 17
KRT4 keratin 4, type II
LAMB2 laminin, beta 2 (laminin S)
LINS lines homolog (Drosophila)
LPAR3 lysophosphatidic acid receptor 3
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
MDFI MyoD family inhibitor
MFGE8 milk fat globule-EGF factor 8 protein
MILR1 mast cell immunoglobulin-like receptor 1
MLYCD malonyl-CoA decarboxylase
MMP13 matrix metallopeptidase 13
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NADSYN1 NAD synthetase 1
NME5 NME/NM23 family member 5
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPM3 nucleophosmin/nucleoplasmin 3
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRR7 proline rich 7 (synaptic)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNF146 ring finger protein 146
RNF2 ring finger protein 2
ROM1 retinal outer segment membrane protein 1
SCAMP5 secretory carrier membrane protein 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNTA1 syntrophin, alpha 1
SPAG4 sperm associated antigen 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THRAP3 thyroid hormone receptor associated protein 3
TMEM132A transmembrane protein 132A
TNS2 tensin 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
ZFHX3 zinc finger homeobox 3
ZMAT5 zinc finger, matrin-type 5
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF385D zinc finger protein 385D
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF623 zinc finger protein 623
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768