| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the cefepime-6159 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALX4 | ALX homeobox 4 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP9B | ATPase, class II, type 9B |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CD47 | CD47 molecule |
| CHGA | chromogranin A |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLEC3B | C-type lectin domain family 3, member B |
| COL11A1 | collagen, type XI, alpha 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL7A1 | collagen, type VII, alpha 1 |
| CREM | cAMP responsive element modulator |
| CRYGC | crystallin, gamma C |
| CTSZ | cathepsin Z |
| CXXC4 | CXXC finger protein 4 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DAO | D-amino-acid oxidase |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP7 | dual specificity phosphatase 7 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| EHD2 | EH-domain containing 2 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FHL1 | four and a half LIM domains 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| HABP4 | hyaluronan binding protein 4 |
| HAP1 | huntingtin-associated protein 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IFNA16 | interferon, alpha 16 |
| IL22 | interleukin 22 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LATS1 | large tumor suppressor kinase 1 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MPDZ | multiple PDZ domain protein |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MTSS1L | metastasis suppressor 1-like |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYL10 | myosin, light chain 10, regulatory |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NEBL | nebulette |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL10 | nucleolar protein 10 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRCAM | neuronal cell adhesion molecule |
| PAPPA2 | pappalysin 2 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| REC8 | REC8 meiotic recombination protein |
| RHEB | Ras homolog enriched in brain |
| RNASE3 | ribonuclease, RNase A family, 3 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC5A4 | solute carrier family 5 (glucose activated ion channel), member 4 |
| SPANXC | SPANX family, member C |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRPK3 | SRSF protein kinase 3 |
| STAB1 | stabilin 1 |
| TAS2R14 | taste receptor, type 2, member 14 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRAV8-3 | T cell receptor alpha variable 8-3 |
| TRD | T cell receptor delta locus |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC9 | tetratricopeptide repeat domain 9 |
| ZER1 | zyg-11 related, cell cycle regulator |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKRD11 | ankyrin repeat domain 11 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CENPJ | centromere protein J |
| CEP97 | centrosomal protein 97kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CLEC2D | C-type lectin domain family 2, member D |
| CRMP1 | collapsin response mediator protein 1 |
| CTSV | cathepsin V |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNM3 | dynamin 3 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GP6 | glycoprotein VI (platelet) |
| GPX2 | glutathione peroxidase 2 |
| GSPT2 | G1 to S phase transition 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4D | histone cluster 1, H4d |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KLF13 | Kruppel-like factor 13 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MIS18BP1 | MIS18 binding protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PENK | proenkephalin |
| PGBD5 | piggyBac transposable element derived 5 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PYGB | phosphorylase, glycogen; brain |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB33A | RAB33A, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SPAG1 | sperm associated antigen 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEX15 | testis expressed 15 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TLR1 | toll-like receptor 1 |
| TNS2 | tensin 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZIC3 | Zic family member 3 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF254 | zinc finger protein 254 |
| ZNF345 | zinc finger protein 345 |
| ZNF480 | zinc finger protein 480 |
