| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cefepime-6237 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| AIM1L | absent in melanoma 1-like |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANGPT4 | angiopoietin 4 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| BCL2A1 | BCL2-related protein A1 |
| BMP4 | bone morphogenetic protein 4 |
| C1QB | complement component 1, q subcomponent, B chain |
| CALML3 | calmodulin-like 3 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CD6 | CD6 molecule |
| CD8B | CD8b molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHN2 | chimerin 2 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCA1 | chloride channel accessory 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CTSZ | cathepsin Z |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DSPP | dentin sialophosphoprotein |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ETNK2 | ethanolamine kinase 2 |
| FAM120C | family with sequence similarity 120C |
| FAM214B | family with sequence similarity 214, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLCN | folliculin |
| FLOT1 | flotillin 1 |
| FRMD1 | FERM domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPC3 | glypican 3 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSPT1 | G1 to S phase transition 1 |
| HCFC1 | host cell factor C1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| ICAM1 | intercellular adhesion molecule 1 |
| IFT54 | intraflagellar transport 54 |
| IL23A | interleukin 23, alpha subunit p19 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRN3 | leucine rich repeat neuronal 3 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYOD1 | myogenic differentiation 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDGFD | platelet derived growth factor D |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRSS53 | protease, serine, 53 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTK6 | protein tyrosine kinase 6 |
| RAB3D | RAB3D, member RAS oncogene family |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPLP2 | ribosomal protein, large, P2 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SFTPC | surfactant protein C |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIX1 | SIX homeobox 1 |
| SNW1 | SNW domain containing 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBX10 | T-box 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TCHH | trichohyalin |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| UTRN | utrophin |
| VASH2 | vasohibin 2 |
| VAX2 | ventral anterior homeobox 2 |
| WSCD1 | WSC domain containing 1 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZNF117 | zinc finger protein 117 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF3 | activating transcription factor 3 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BBC3 | BCL2 binding component 3 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CLDND1 | claudin domain containing 1 |
| CLK2 | CDC-like kinase 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COCH | cochlin |
| COG4 | component of oligomeric golgi complex 4 |
| CXORF56 | chromosome X open reading frame 56 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DSE | dermatan sulfate epimerase |
| DUSP8 | dual specificity phosphatase 8 |
| EVPL | envoplakin |
| EXOC5 | exocyst complex component 5 |
| FA2H | fatty acid 2-hydroxylase |
| FANCC | Fanconi anemia, complementation group C |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FOXK2 | forkhead box K2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| INO80D | INO80 complex subunit D |
| INSIG2 | insulin induced gene 2 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0753 | KIAA0753 |
| KIAA0894 | KIAA0894 protein |
| KRBOX4 | KRAB box domain containing 4 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC642236 | FSHD region gene 1 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEH1 | melanoma antigen family H1 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MMP9 | matrix metallopeptidase 9 |
| MPI | mannose phosphate isomerase |
| MYO9A | myosin IXA |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OCEL1 | occludin/ELL domain containing 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PLD3 | phospholipase D family, member 3 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POR | P450 (cytochrome) oxidoreductase |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF31 | ring finger protein 31 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| RWDD2A | RWD domain containing 2A |
| SETD6 | SET domain containing 6 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SNAI2 | snail family zinc finger 2 |
| SQRDL | sulfide quinone reductase-like (yeast) |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSFA2 | sperm specific antigen 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TDRD1 | tudor domain containing 1 |
| TGDS | TDP-glucose 4,6-dehydratase |
| TMEM127 | transmembrane protein 127 |
| TMEM260 | transmembrane protein 260 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM66 | tripartite motif containing 66 |
| UBXN6 | UBX domain protein 6 |
| USP36 | ubiquitin specific peptidase 36 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WASF2 | WAS protein family, member 2 |
| WDR13 | WD repeat domain 13 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF302 | zinc finger protein 302 |
| ZNF354A | zinc finger protein 354A |
| ZNF408 | zinc finger protein 408 |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |
| ZNF768 | zinc finger protein 768 |
| ZNF8 | zinc finger protein 8 |