cefixime-1310 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefixime-1310 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACOX2 acyl-CoA oxidase 2, branched chain
ADCY3 adenylate cyclase 3
ANKRD12 ankyrin repeat domain 12
ANKRD26 ankyrin repeat domain 26
ARHGAP44 Rho GTPase activating protein 44
BAHCC1 BAH domain and coiled-coil containing 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
CBX4 chromobox homolog 4
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSZ cathepsin Z
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DMXL2 Dmx-like 2
E2F4 E2F transcription factor 4, p107/p130-binding
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EXOC7 exocyst complex component 7
FAM168A family with sequence similarity 168, member A
FAM214B family with sequence similarity 214, member B
FAM49A family with sequence similarity 49, member A
GFOD2 glucose-fructose oxidoreductase domain containing 2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H2BI histone cluster 1, H2bi
HMGN5 high mobility group nucleosome binding domain 5
HNRNPL heterogeneous nuclear ribonucleoprotein L
IDS iduronate 2-sulfatase
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
IQCC IQ motif containing C
IVL involucrin
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF3C kinesin family member 3C
LDB1 LIM domain binding 1
LIMD2 LIM domain containing 2
LMNB1 lamin B1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTB4R leukotriene B4 receptor
LY6E lymphocyte antigen 6 complex, locus E
LZTR1 leucine-zipper-like transcription regulator 1
MAP4 microtubule-associated protein 4
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MBD4 methyl-CpG binding domain protein 4
MKL1 megakaryoblastic leukemia (translocation) 1
MON2 MON2 homolog (S. cerevisiae)
MTA1 metastasis associated 1
NF1 neurofibromin 1
NMT1 N-myristoyltransferase 1
NSUN6 NOP2/Sun domain family, member 6
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP54 nucleoporin 54kDa
PARG poly (ADP-ribose) glycohydrolase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCGF2 polycomb group ring finger 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER1 period circadian clock 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPARD peroxisome proliferator-activated receptor delta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRAF2 PRA1 domain family, member 2
PRR4 proline rich 4 (lacrimal)
RECQL5 RecQ protein-like 5
REL v-rel avian reticuloendotheliosis viral oncogene homolog
SCAPER S-phase cyclin A-associated protein in the ER
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SETD6 SET domain containing 6
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX4 SRY (sex determining region Y)-box 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH3 slingshot protein phosphatase 3
STK19 serine/threonine kinase 19
SYNJ2 synaptojanin 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D4 TBC1 domain family, member 4
TCF3 transcription factor 3
TCOF1 Treacher Collins-Franceschetti syndrome 1
TDRD3 tudor domain containing 3
TIMELESS timeless circadian clock
TPMT thiopurine S-methyltransferase
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TRIM68 tripartite motif containing 68
TSPAN13 tetraspanin 13
TXNL4A thioredoxin-like 4A
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UST uronyl-2-sulfotransferase
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZDHHC24 zinc finger, DHHC-type containing 24
ZMYND8 zinc finger, MYND-type containing 8
ZNF337 zinc finger protein 337
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AAMP angio-associated, migratory cell protein
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD17B abhydrolase domain containing 17B
ACP6 acid phosphatase 6, lysophosphatidic
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AMIGO2 adhesion molecule with Ig-like domain 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P2 annexin A2 pseudogene 2
ANXA3 annexin A3
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC2 apolipoprotein C-II
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASB6 ankyrin repeat and SOCS box containing 6
BAHD1 bromo adjacent homology domain containing 1
BPI bactericidal/permeability-increasing protein
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD18 BTB (POZ) domain containing 18
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C17ORF85 chromosome 17 open reading frame 85
C8ORF44 chromosome 8 open reading frame 44
CEP131 centrosomal protein 131kDa
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COMMD9 COMM domain containing 9
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPY19L2P2 DPY19L2 pseudogene 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERCC2 excision repair cross-complementation group 2
FAM188A family with sequence similarity 188, member A
FAM222B family with sequence similarity 222, member B
FKBP9 FK506 binding protein 9, 63 kDa
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEMIN8 gem (nuclear organelle) associated protein 8
GRWD1 glutamate-rich WD repeat containing 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTPBP3 GTP binding protein 3 (mitochondrial)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFT81 intraflagellar transport 81
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LIG4 ligase IV, DNA, ATP-dependent
LINC00597 long intergenic non-protein coding RNA 597
LRRK1 leucine-rich repeat kinase 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEB2 melanoma antigen family B2
MANEA mannosidase, endo-alpha
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOGS mannosyl-oligosaccharide glucosidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYL5 myosin, light chain 5, regulatory
NHEJ1 nonhomologous end-joining factor 1
NPFFR1 neuropeptide FF receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSD1 nuclear receptor binding SET domain protein 1
ODF2 outer dense fiber of sperm tails 2
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMM1 phosphomannomutase 1
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PSKH1 protein serine kinase H1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PYCR1 pyrroline-5-carboxylate reductase 1
RAB23 RAB23, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOC ras homolog family member C
RNF122 ring finger protein 122
RRAS related RAS viral (r-ras) oncogene homolog
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SIRAL2 SIR2 antiphage like 2
SLITRK5 SLIT and NTRK-like family, member 5
SNHG20 small nucleolar RNA host gene 20
SNRPN small nuclear ribonucleoprotein polypeptide N
SPRYD7 SPRY domain containing 7
TBC1D17 TBC1 domain family, member 17
TCTN2 tectonic family member 2
TGM5 transglutaminase 5
THBS3 thrombospondin 3
TM9SF4 transmembrane 9 superfamily protein member 4
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM115 transmembrane protein 115
TMEM62 transmembrane protein 62
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNNT1 troponin T type 1 (skeletal, slow)
TRAPPC13 trafficking protein particle complex 13
TRIM25 tripartite motif containing 25
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
TXNL4B thioredoxin-like 4B
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
WT1-AS WT1 antisense RNA
ZBTB3 zinc finger and BTB domain containing 3
ZBTB6 zinc finger and BTB domain containing 6
ZC3H3 zinc finger CCCH-type containing 3
ZNF34 zinc finger protein 34