| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cefixime-4390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAM18 | ADAM metallopeptidase domain 18 |
| AGTR2 | angiotensin II receptor, type 2 |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| ASMT | acetylserotonin O-methyltransferase |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BGN | biglycan |
| BST1 | bone marrow stromal cell antigen 1 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC57 | coiled-coil domain containing 57 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CFAP69 | cilia and flagella associated protein 69 |
| CLIC5 | chloride intracellular channel 5 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL13A1 | collagen, type XIII, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCN | decorin |
| DOK2 | docking protein 2, 56kDa |
| ELN | elastin |
| EPHA5 | EPH receptor A5 |
| EXPH5 | exophilin 5 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FCAR | Fc fragment of IgA receptor |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FFAR3 | free fatty acid receptor 3 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF23 | fibroblast growth factor 23 |
| FHL5 | four and a half LIM domains 5 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GPR4 | G protein-coupled receptor 4 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HHIPL2 | HHIP-like 2 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXB6 | homeobox B6 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIAA1462 | KIAA1462 |
| KRT75 | keratin 75, type II |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LPL | lipoprotein lipase |
| MAOA | monoamine oxidase A |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXD1 | MAX dimerization protein 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYO9B | myosin IXB |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| PARVB | parvin, beta |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PTAFR | platelet-activating factor receptor |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RCAN2 | regulator of calcineurin 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RUNX1 | runt-related transcription factor 1 |
| SCARF1 | scavenger receptor class F, member 1 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD6 | SMAD family member 6 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SV2A | synaptic vesicle glycoprotein 2A |
| SYT5 | synaptotagmin V |
| TAT | tyrosine aminotransferase |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TP63 | tumor protein p63 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TUBB7P | tubulin, beta 7, pseudogene |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| VNN2 | vanin 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| AMT | aminomethyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BAGE | B melanoma antigen |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC109B | coiled-coil domain containing 109B |
| CD2AP | CD2-associated protein |
| CDK20 | cyclin-dependent kinase 20 |
| CENPJ | centromere protein J |
| CES3 | carboxylesterase 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CORT | cortistatin |
| CRY1 | cryptochrome circadian clock 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DOCK1 | dedicator of cytokinesis 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GRAMD1C | GRAM domain containing 1C |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HOXB2 | homeobox B2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL17RA | interleukin 17 receptor A |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMNB1 | lamin B1 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MFAP2 | microfibrillar-associated protein 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MTCP1 | mature T-cell proliferation 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MTMR6 | myotubularin related protein 6 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHA6 | protocadherin alpha 6 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POLL | polymerase (DNA directed), lambda |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK6 | protein tyrosine kinase 6 |
| RAB5B | RAB5B, member RAS oncogene family |
| RNF43 | ring finger protein 43 |
| SCHIP1 | schwannomin interacting protein 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNTA1 | syntrophin, alpha 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STRA6 | stimulated by retinoic acid 6 |
| STRN | striatin, calmodulin binding protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TPSG1 | tryptase gamma 1 |
| TRAIP | TRAF interacting protein |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBTD1 | ubiquitin domain containing 1 |
| VLDLR | very low density lipoprotein receptor |
| XK | X-linked Kx blood group |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF141 | zinc finger protein 141 |
| ZW10 | zw10 kinetochore protein |
