cefmetazole-5868 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefmetazole-5868 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
C9ORF9 chromosome 9 open reading frame 9
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFLAR CASP8 and FADD-like apoptosis regulator
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL21A1 collagen, type XXI, alpha 1
COL2A1 collagen, type II, alpha 1
CSPP1 centrosome and spindle pole associated protein 1
DDO D-aspartate oxidase
DNAL4 dynein, axonemal, light chain 4
DOPEY2 dopey family member 2
EDN1 endothelin 1
EFS embryonal Fyn-associated substrate
EIF3F eukaryotic translation initiation factor 3, subunit F
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELMO2 engulfment and cell motility 2
EML3 echinoderm microtubule associated protein like 3
ETV1 ets variant 1
FLJ11292
FSCN3 fascin actin-bundling protein 3, testicular
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAP43 growth associated protein 43
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLRA1 glycine receptor, alpha 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
HAUS5 HAUS augmin-like complex, subunit 5
HIC2 hypermethylated in cancer 2
HIPK3 homeodomain interacting protein kinase 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HYAL3 hyaluronoglucosaminidase 3
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNA16 interferon, alpha 16
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHM immunoglobulin heavy constant mu
INO80B INO80 complex subunit B
INSL6 insulin-like 6
KDM5C lysine (K)-specific demethylase 5C
KHK ketohexokinase (fructokinase)
KIF25-AS1 KIF25 antisense RNA 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT83 keratin 83, type II
LMAN1 lectin, mannose-binding, 1
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
METTL7A methyltransferase like 7A
MFGE8 milk fat globule-EGF factor 8 protein
MYL10 myosin, light chain 10, regulatory
MYRF myelin regulatory factor
MZF1 myeloid zinc finger 1
NPY neuropeptide Y
ODAM odontogenic, ameloblast asssociated
ORAI2 ORAI calcium release-activated calcium modulator 2
PAOX polyamine oxidase (exo-N4-amino)
PCDH11Y protocadherin 11 Y-linked
PER2 period circadian clock 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD54B RAD54 homolog B (S. cerevisiae)
RARG retinoic acid receptor, gamma
RCE1 Ras converting CAAX endopeptidase 1
RHOBTB2 Rho-related BTB domain containing 2
RUNX1 runt-related transcription factor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC16A6 solute carrier family 16, member 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC1A structural maintenance of chromosomes 1A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAC SH3 and cysteine rich domain
STX3 syntaxin 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TM2D1 TM2 domain containing 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TPR translocated promoter region, nuclear basket protein
UBE3B ubiquitin protein ligase E3B
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VGLL3 vestigial-like family member 3
WDTC1 WD and tetratricopeptide repeats 1
WIZ widely interspaced zinc finger motifs
YY1 YY1 transcription factor
ZNF589 zinc finger protein 589
ZNF767P zinc finger family member 767, pseudogene
ZNF783 zinc finger family member 783
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
APOLD1 apolipoprotein L domain containing 1
ARL14 ADP-ribosylation factor-like 14
ATAD3A ATPase family, AAA domain containing 3A
ATG7 autophagy related 7
ATP13A2 ATPase type 13A2
BAK1 BCL2-antagonist/killer 1
BEX1 brain expressed, X-linked 1
BRWD1 bromodomain and WD repeat domain containing 1
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C1ORF112 chromosome 1 open reading frame 112
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CCDC68 coiled-coil domain containing 68
CDKN2AIP CDKN2A interacting protein
CNTNAP3B contactin associated protein-like 3B
COMMD8 COMM domain containing 8
COQ4 coenzyme Q4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYBA2 crystallin, beta A2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DEAF1 DEAF1 transcription factor
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DPH2 DPH2 homolog (S. cerevisiae)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGLN2 egl-9 family hypoxia-inducible factor 2
ERMP1 endoplasmic reticulum metallopeptidase 1
FOXC1 forkhead box C1
GAA glucosidase, alpha; acid
GID4 GID complex subunit 4
GLCE glucuronic acid epimerase
GPATCH2 G patch domain containing 2
GPATCH3 G patch domain containing 3
HAMP hepcidin antimicrobial peptide
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
HOXC4 homeobox C4
HPS6 Hermansky-Pudlak syndrome 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL10RB interleukin 10 receptor, beta
IL4R interleukin 4 receptor
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK4 interleukin-1 receptor-associated kinase 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT15 keratin 15, type I
LPAR3 lysophosphatidic acid receptor 3
MAGEH1 melanoma antigen family H1
MBTD1 mbt domain containing 1
MEX3C mex-3 RNA binding family member C
MITF microphthalmia-associated transcription factor
MTG1 mitochondrial ribosome-associated GTPase 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NINJ1 ninjurin 1
NOL12 nucleolar protein 12
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCEL1 occludin/ELL domain containing 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P3H2 prolyl 3-hydroxylase 2
PARD6A par-6 family cell polarity regulator alpha
PCID2 PCI domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PEX10 peroxisomal biogenesis factor 10
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLM polymerase (DNA directed), mu
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM4B RNA binding motif protein 4B
RIN1 Ras and Rab interactor 1
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SND1-IT1 SND1 intronic transcript 1
SNORA21 small nucleolar RNA, H/ACA box 21
SNX15 sorting nexin 15
TAGLN3 transgelin 3
TBC1D19 TBC1 domain family, member 19
TGFB3 transforming growth factor, beta 3
TMEM209 transmembrane protein 209
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
TTC23 tetratricopeptide repeat domain 23
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
ZBTB10 zinc finger and BTB domain containing 10
ZBTB39 zinc finger and BTB domain containing 39
ZFHX3 zinc finger homeobox 3
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324
ZNF571 zinc finger protein 571
ZNF813 zinc finger protein 813
ZXDC ZXD family zinc finger C