cefoperazone-1627 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cefoperazone-1627 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALAD aminolevulinate dehydratase
ALDOC aldolase C, fructose-bisphosphate
ARG1 arginase 1
ARHGAP33 Rho GTPase activating protein 33
ARRB2 arrestin, beta 2
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP10A ATPase, class V, type 10A
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2A1 BCL2-related protein A1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPI bactericidal/permeability-increasing protein
BST1 bone marrow stromal cell antigen 1
BTG1 B-cell translocation gene 1, anti-proliferative
C2CD2L C2CD2-like
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CD164 CD164 molecule, sialomucin
CD300A CD300a molecule
CD86 CD86 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEP152 centrosomal protein 152kDa
CIZ1 CDKN1A interacting zinc finger protein 1
CKB creatine kinase, brain
CRYBB2P1 crystallin, beta B2 pseudogene 1
CS citrate synthase
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
EFHC1 EF-hand domain (C-terminal) containing 1
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ENO2 enolase 2 (gamma, neuronal)
EPHB1 EPH receptor B1
FAM114A2 family with sequence similarity 114, member A2
FAM188A family with sequence similarity 188, member A
FBXL18 F-box and leucine-rich repeat protein 18
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FTH1 ferritin, heavy polypeptide 1
GBP2 guanylate binding protein 2, interferon-inducible
GPR107 G protein-coupled receptor 107
GPR183 G protein-coupled receptor 183
HPCAL1 hippocalcin-like 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDS iduronate 2-sulfatase
IFI16 interferon, gamma-inducible protein 16
IL27RA interleukin 27 receptor, alpha
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KCTD3 potassium channel tetramerization domain containing 3
KDM4B lysine (K)-specific demethylase 4B
KLF10 Kruppel-like factor 10
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NCOA3 nuclear receptor coactivator 3
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRP1 neuropilin 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGFR opioid growth factor receptor
PCNX pecanex homolog (Drosophila)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE8A phosphodiesterase 8A
PDLIM7 PDZ and LIM domain 7 (enigma)
PECAM1 platelet/endothelial cell adhesion molecule 1
PITPNA phosphatidylinositol transfer protein, alpha
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLIN2 perilipin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POR P450 (cytochrome) oxidoreductase
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTCRA pre T-cell antigen receptor alpha
RAB28 RAB28, member RAS oncogene family
RAD1 RAD1 checkpoint DNA exonuclease
RALY RALY heterogeneous nuclear ribonucleoprotein
RBKS ribokinase
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SFXN3 sideroflexin 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLK STE20-like kinase
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPP1 secreted phosphoprotein 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TMEM156 transmembrane protein 156
TMEM45A transmembrane protein 45A
TOX4 TOX high mobility group box family member 4
UHRF1BP1L UHRF1 binding protein 1-like
UNC119B unc-119 homolog B (C. elegans)
UPB1 ureidopropionase, beta
WDR91 WD repeat domain 91
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB20 zinc finger and BTB domain containing 20
ZNF134 zinc finger protein 134
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACOT9 acyl-CoA thioesterase 9
ANAPC2 anaphase promoting complex subunit 2
APOBR apolipoprotein B receptor
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP10 Rho GTPase activating protein 10
ASTE1 asteroid homolog 1 (Drosophila)
AUH AU RNA binding protein/enoyl-CoA hydratase
B3GNT1
BBC3 BCL2 binding component 3
BCCIP BRCA2 and CDKN1A interacting protein
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BEX1 brain expressed, X-linked 1
C10ORF2 chromosome 10 open reading frame 2
C11ORF48
CAPN1 calpain 1, (mu/I) large subunit
CD151 CD151 molecule (Raph blood group)
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CINP cyclin-dependent kinase 2 interacting protein
CLDN15 claudin 15
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNTD2 cyclin N-terminal domain containing 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEXI Dexi homolog (mouse)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPH2 DPH2 homolog (S. cerevisiae)
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ELP4 elongator acetyltransferase complex subunit 4
ERCC2 excision repair cross-complementation group 2
ERF Ets2 repressor factor
FBXL4 F-box and leucine-rich repeat protein 4
FTO fat mass and obesity associated
GIN1 gypsy retrotransposon integrase 1
GLRX5 glutaredoxin 5
GPS1 G protein pathway suppressor 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HK1 hexokinase 1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IL4R interleukin 4 receptor
ILK integrin-linked kinase
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS9 lectin, galactoside-binding, soluble, 9
LIAS lipoic acid synthetase
LMAN2L lectin, mannose-binding 2-like
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NUBP1 nucleotide binding protein 1
NUBP2 nucleotide binding protein 2
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP93 nucleoporin 93kDa
NUTF2 nuclear transport factor 2
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRMT3 protein arginine methyltransferase 3
PRTN3 proteinase 3
PSKH1 protein serine kinase H1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPRT quinolinate phosphoribosyltransferase
RBM14 RNA binding motif protein 14
RFK riboflavin kinase
RNF123 ring finger protein 123
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSBN1 round spermatid basic protein 1
RWDD2B RWD domain containing 2B
SAMHD1 SAM domain and HD domain 1
SCRIB scribbled planar cell polarity protein
SFT2D2 SFT2 domain containing 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SNRPC small nuclear ribonucleoprotein polypeptide C
TCTN2 tectonic family member 2
TFB2M transcription factor B2, mitochondrial
THAP1 THAP domain containing, apoptosis associated protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM168 transmembrane protein 168
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D1 TSC22 domain family, member 1
TSLIG2 tRNA splicing ligase complex subunit 2
TSPAN32 tetraspanin 32
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGDH UDP-glucose 6-dehydrogenase
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
WDR3 WD repeat domain 3
WWC2 WW and C2 domain containing 2
ZNF16 zinc finger protein 16
ZNF432 zinc finger protein 432
ZPR1 ZPR1 zinc finger