| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cefotaxime-2072 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACACB | acetyl-CoA carboxylase beta |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit |
| APOL2 | apolipoprotein L, 2 |
| APOM | apolipoprotein M |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAX | BCL2-associated X protein |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1R | complement component 1, r subcomponent |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC101 | coiled-coil domain containing 101 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP68 | centrosomal protein 68kDa |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| COL7A1 | collagen, type VII, alpha 1 |
| CTSZ | cathepsin Z |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNPEP | aspartyl aminopeptidase |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGR1 | early growth response 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMID1 | EMI domain containing 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPS8L1 | EPS8-like 1 |
| EXOC6B | exocyst complex component 6B |
| FCF1 | FCF1 rRNA-processing protein |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLOT1 | flotillin 1 |
| GPR17 | G protein-coupled receptor 17 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSDMD | gasdermin D |
| GSR | glutathione reductase |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H2AM | histone cluster 1, H2am |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXB5 | homeobox B5 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INTS7 | integrator complex subunit 7 |
| ITGB5 | integrin, beta 5 |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KRT17 | keratin 17, type I |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC81691 | exonuclease NEF-sp |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAX | MYC associated factor X |
| MIIP | migration and invasion inhibitory protein |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| NCOA2 | nuclear receptor coactivator 2 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEK1 | NIMA-related kinase 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NKTR | natural killer cell triggering receptor |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PALM | paralemmin |
| PASK | PAS domain containing serine/threonine kinase |
| PEG3 | paternally expressed 3 |
| PFDN6 | prefoldin subunit 6 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRDM12 | PR domain containing 12 |
| RAB11B | RAB11B, member RAS oncogene family |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF126 | ring finger protein 126 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SETD2 | SET domain containing 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D30 | TBC1 domain family, member 30 |
| TEX261 | testis expressed 261 |
| TLE4 | transducin-like enhancer of split 4 |
| TLN2 | talin 2 |
| TMEM38B | transmembrane protein 38B |
| TSPAN9 | tetraspanin 9 |
| TWIST1 | twist family bHLH transcription factor 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALPK1 | alpha-kinase 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOO | apolipoprotein O |
| ARRB2 | arrestin, beta 2 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BMP15 | bone morphogenetic protein 15 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD70 | CD70 molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CENPQ | centromere protein Q |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLK3 | CDC-like kinase 3 |
| COMMD10 | COMM domain containing 10 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| EVL | Enah/Vasp-like |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPHN | gephyrin |
| GPR176 | G protein-coupled receptor 176 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HOXC13 | homeobox C13 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYI | hydroxypyruvate isomerase (putative) |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL32 | interleukin 32 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0753 | KIAA0753 |
| KIZ | kizuna centrosomal protein |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MATN3 | matrilin 3 |
| MB | myoglobin |
| MED15 | mediator complex subunit 15 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MKS1 | Meckel syndrome, type 1 |
| MMP13 | matrix metallopeptidase 13 |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NGF | nerve growth factor (beta polypeptide) |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRAME | preferentially expressed antigen in melanoma |
| RAB3A | RAB3A, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RNF170 | ring finger protein 170 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SELENBP1 | selenium binding protein 1 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMAD7 | SMAD family member 7 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAG3 | stromal antigen 3 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX19 | T-box 19 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRAIP | TRAF interacting protein |
| TREX1 | three prime repair exonuclease 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| USP18 | ubiquitin specific peptidase 18 |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR33 | WD repeat domain 33 |
| ZNF212 | zinc finger protein 212 |
| ZNF254 | zinc finger protein 254 |
| ZNF324 | zinc finger protein 324 |
| ZNF35 | zinc finger protein 35 |
