cefotaxime-2235 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the cefotaxime-2235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADORA3 adenosine A3 receptor
AGFG2 ArfGAP with FG repeats 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP3 BAI1-associated protein 3
C19ORF66 chromosome 19 open reading frame 66
C8B complement component 8, beta polypeptide
CALD1 caldesmon 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CD207 CD207 molecule, langerin
CD28 CD28 molecule
CIITA class II, major histocompatibility complex, transactivator
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CUX2 cut-like homeobox 2
CXCR6 chemokine (C-X-C motif) receptor 6
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DGCR8 DGCR8 microprocessor complex subunit
DOK4 docking protein 4
ECEL1 endothelin converting enzyme-like 1
ERCC4 excision repair cross-complementation group 4
FAM214B family with sequence similarity 214, member B
FAM76A family with sequence similarity 76, member A
FBLN1 fibulin 1
FGF4 fibroblast growth factor 4
FN1 fibronectin 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATA2 GATA binding protein 2
GK2 glycerol kinase 2
GREB1 growth regulation by estrogen in breast cancer 1
HFE hemochromatosis
HIST1H1E histone cluster 1, H1e
HNF1B HNF1 homeobox B
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IMPG2 interphotoreceptor matrix proteoglycan 2
INE1 inactivation escape 1 (non-protein coding)
INO80D INO80 complex subunit D
KRT8 keratin 8, type II
LAG3 lymphocyte-activation gene 3
LAMP1 lysosomal-associated membrane protein 1
LDLR low density lipoprotein receptor
LOC441601 septin 7 pseudogene
LTBP2 latent transforming growth factor beta binding protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MAP2K5 mitogen-activated protein kinase kinase 5
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKL1 megakaryoblastic leukemia (translocation) 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOCS1 molybdenum cofactor synthesis 1
NEFM neurofilament, medium polypeptide
NELL2 NEL-like 2 (chicken)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
OAZ3 ornithine decarboxylase antizyme 3
ONECUT2 one cut homeobox 2
PLK3 polo-like kinase 3
PPARA peroxisome proliferator-activated receptor alpha
PROSC proline synthetase co-transcribed homolog (bacterial)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RABGAP1L RAB GTPase activating protein 1-like
RAD52 RAD52 homolog (S. cerevisiae)
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SDC2 syndecan 2
SFTPC surfactant protein C
SKIL SKI-like proto-oncogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
SPTBN5 spectrin, beta, non-erythrocytic 5
SUGP1 SURP and G patch domain containing 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF12 transcription factor 12
TENM4 teneurin transmembrane protein 4
TPSG1 tryptase gamma 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTC38 tetratricopeptide repeat domain 38
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VN1R1 vomeronasal 1 receptor 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZC3H13 zinc finger CCCH-type containing 13
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARMC4 armadillo repeat containing 4
BMP4 bone morphogenetic protein 4
C2ORF44 chromosome 2 open reading frame 44
C3 complement component 3
C5AR2 complement component 5a receptor 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CEL carboxyl ester lipase
CIC capicua transcriptional repressor
CSF1R colony stimulating factor 1 receptor
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
FEM1C fem-1 homolog c (C. elegans)
FOCAD focadhesin
FSTL3 follistatin-like 3 (secreted glycoprotein)
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTM5 glutathione S-transferase mu 5
HDAC11 histone deacetylase 11
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
IMPACT impact RWD domain protein
INF2 inverted formin, FH2 and WH2 domain containing
INPP1 inositol polyphosphate-1-phosphatase
IQCG IQ motif containing G
IRF2 interferon regulatory factor 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MARC1 mitochondrial amidoxime reducing component 1
MBTD1 mbt domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF1 mitochondrial transcription termination factor 1
MYO1D myosin ID
MYOZ1 myozenin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NPIPB15 nuclear pore complex interacting protein family, member B15
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA6 protocadherin alpha 6
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PNPLA6 patatin-like phospholipase domain containing 6
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRODH proline dehydrogenase (oxidase) 1
PTCD2 pentatricopeptide repeat domain 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB5B RAB5B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF208 ring finger protein 208
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE2 signal peptide, CUB domain, EGF-like 2
SIPA1 signal-induced proliferation-associated 1
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
STX5 syntaxin 5
TEAD3 TEA domain family member 3
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TRIM66 tripartite motif containing 66
TTLL1 tubulin tyrosine ligase-like family member 1
TWF2 twinfilin actin binding protein 2
UBTD1 ubiquitin domain containing 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZIC3 Zic family member 3
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF668 zinc finger protein 668