| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the cefotaxime-5830 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACVR1B | activin A receptor, type IB |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CALD1 | caldesmon 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDC42 | cell division cycle 42 |
| CES3 | carboxylesterase 3 |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CNTN1 | contactin 1 |
| COMMD4 | COMM domain containing 4 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DLG3 | discs, large homolog 3 (Drosophila) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOK5 | docking protein 5 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM205BP | transmembrane protein C9orf144B pseudogene |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FYB | FYN binding protein |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPM6A | glycoprotein M6A |
| GPSM3 | G-protein signaling modulator 3 |
| GPX2 | glutathione peroxidase 2 |
| GTPBP4 | GTP binding protein 4 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC10 | homeobox C10 |
| INADL | InaD-like (Drosophila) |
| IRF9 | interferon regulatory factor 9 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIF1A | kinesin family member 1A |
| KIF5C | kinesin family member 5C |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT75 | keratin 75, type II |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAGEA5 | melanoma antigen family A5 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METTL16 | methyltransferase like 16 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTUD4 | OTU deubiquitinase 4 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAPPA2 | pappalysin 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLK3 | polo-like kinase 3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RAB3B | RAB3B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RASAL2 | RAS protein activator like 2 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RNF122 | ring finger protein 122 |
| RTN2 | reticulon 2 |
| RUNX1 | runt-related transcription factor 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCRN3 | secernin 3 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SSH3 | slingshot protein phosphatase 3 |
| TAGLN3 | transgelin 3 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TEX40 | testis expressed 40 |
| TLN2 | talin 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNC | tenascin C |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRAF4 | TNF receptor-associated factor 4 |
| TSPAN31 | tetraspanin 31 |
| TUBA4B | tubulin, alpha 4b |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| USP20 | ubiquitin specific peptidase 20 |
| WBP4 | WW domain binding protein 4 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF529 | zinc finger protein 529 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACOT8 | acyl-CoA thioesterase 8 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AK5 | adenylate kinase 5 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARMC6 | armadillo repeat containing 6 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BDNF | brain-derived neurotrophic factor |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASZ1 | castor zinc finger 1 |
| CDC37L1 | cell division cycle 37-like 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH7 | cadherin 7, type 2 |
| CEP112 | centrosomal protein 112kDa |
| CEP170B | centrosomal protein 170B |
| CFAP69 | cilia and flagella associated protein 69 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDN | dendrin |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DUSP8 | dual specificity phosphatase 8 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPPK1 | epiplakin 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| HIRA | histone cell cycle regulator |
| HIRIP3 | HIRA interacting protein 3 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AM | histone cluster 1, H2am |
| HMOX1 | heme oxygenase 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL15RA | interleukin 15 receptor, alpha |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KRT15 | keratin 15, type I |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP1S | microtubule-associated protein 1S |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN1 | mucolipin 1 |
| MMP9 | matrix metallopeptidase 9 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MUC3B | mucin 3B, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXRA8 | matrix-remodelling associated 8 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1D | myosin ID |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDGFD | platelet derived growth factor D |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRPH | peripherin |
| RAB27B | RAB27B, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBM38 | RNA binding motif protein 38 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RWDD3 | RWD domain containing 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNPH | syntaphilin |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| STEAP4 | STEAP family member 4 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN2 | tectonic family member 2 |
| TNNI3 | troponin I type 3 (cardiac) |
| TNS2 | tensin 2 |
| TOR4A | torsin family 4, member A |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| URGCP | upregulator of cell proliferation |
| USB1 | U6 snRNA biogenesis 1 |
| WDR91 | WD repeat domain 91 |
| XAB2 | XPA binding protein 2 |
| ZNF23 | zinc finger protein 23 |
| ZNF446 | zinc finger protein 446 |
| ZNF528 | zinc finger protein 528 |
| ZNF652 | zinc finger protein 652 |
