| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the cefotaxime-7186 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| APC | adenomatous polyposis coli |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BMP2K | BMP2 inducible kinase |
| BRD4 | bromodomain containing 4 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC186 | coiled-coil domain containing 186 |
| CDHR2 | cadherin-related family member 2 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CHML | choroideremia-like (Rab escort protein 2) |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBN1 | drebrin 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DTNA | dystrobrevin, alpha |
| EPOR | erythropoietin receptor |
| ESR1 | estrogen receptor 1 |
| EXOC5 | exocyst complex component 5 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM169A | family with sequence similarity 169, member A |
| FLOT1 | flotillin 1 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BC | histone cluster 1, H2bc |
| HLA-C | major histocompatibility complex, class I, C |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| IFT54 | intraflagellar transport 54 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ITGB4 | integrin, beta 4 |
| ITM2B | integral membrane protein 2B |
| KRT19P2 | keratin 19 pseudogene 2 |
| KRT75 | keratin 75, type II |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MICALL1 | MICAL-like 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUP188 | nucleoporin 188kDa |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCM1 | pericentriolar material 1 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRPH | peripherin |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RCAN1 | regulator of calcineurin 1 |
| RHOQ | ras homolog family member Q |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SKIL | SKI-like proto-oncogene |
| SND1-IT1 | SND1 intronic transcript 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SSPN | sarcospan |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TEP1 | telomerase-associated protein 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIM29 | tripartite motif containing 29 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TXNL4A | thioredoxin-like 4A |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF451 | zinc finger protein 451 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB2 | arrestin, beta 2 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CASKIN2 | CASK interacting protein 2 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHKB | choline kinase beta |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCLRE1A | DNA cross-link repair 1A |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSPP | dentin sialophosphoprotein |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EPHA2 | EPH receptor A2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FBXO46 | F-box protein 46 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLI3 | GLI family zinc finger 3 |
| GPATCH3 | G patch domain containing 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC11 | homeobox C11 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JRKL | JRK-like |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0319L | KIAA0319-like |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP1S | microtubule-associated protein 1S |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED9 | mediator complex subunit 9 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1D | myosin ID |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SALL2 | spalt-like transcription factor 2 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SH2D4A | SH2 domain containing 4A |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STAG3 | stromal antigen 3 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBX19 | T-box 19 |
| TLR5 | toll-like receptor 5 |
| TMC5 | transmembrane channel-like 5 |
| TRIM25 | tripartite motif containing 25 |
| TRIM26 | tripartite motif containing 26 |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VGF | VGF nerve growth factor inducible |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF254 | zinc finger protein 254 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |